- Search results for K04409
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95 products were found matching "K04409"!
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Item number: A301-259A
Protein function: Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes. Can directly...
Keywords: | Anti-PAK1, Anti-PAK-1, Anti-p65-PAK, Anti-Alpha-PAK, EC=2.7.11.1, Anti-p21-activated kinase 1,... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: Cay14759-5
IPA-3 is an allosteric inhibitor of p21-activated kinase 1 (PAK1) activation (IC50 = 2.5 µM) that does not inhibit pre-activated PAK1. It selectively inhibits activation of the group I PAKs, PAK1, PAK2, and PAK3 over the group II PAKs, PAK4, PAK5, and PAK6 at 10 µM. IPA-3 inhibits the severe acute respiratory...
Keywords: | 1,1'-dithiobis-2-naphthalenol |
Application: | PAK1 inhibitor |
CAS | 42521-82-4 |
MW: | 350.5 D |
From 77.00€
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Item number: Cay19964-5
NVS-PAK1-1 is an allosteric inhibitor of p21-activated kinase 1 (PAK1), a non-receptor serine/threonine kinase involved in tumorigenesis (Kd = 7 nM). It has an IC50 value of 5.2 nM in a PAK1 dephosphorylation assay. NVS-PAK1-1 is selective for PAK1 over PAK2 (Kd = 400 nM) and over a panel of 442 kinases, where it...
Keywords: | (3S)-3-[[2-chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-yl]amino]-N-(1-methylethyl)-1-pyrrolidine... |
Application: | Allosteric PAK1 inhibitor |
CAS | 1783816-74-9 |
MW: | 479.9 D |
From 163.00€
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Item number: Cay20711-1
FRAX1036 is a selective inhibitor of p21-activated kinase 1 (PAK1), a serine/threonine kinase downstream of Rac1 and Cdc42 that is involved in tumorigenesis. It can induce apoptosis in breast cancer cells and has been shown to potentiate the activity of the microtubule stabilizing agent, docetaxel (Cay-11637)....
Keywords: | 6-[2-chloro-4-(6-methyl-2-pyrazinyl)phenyl]-8-ethyl-2-[[2-(1-methyl-4-piperidinyl)ethyl]amino]-pyrido[2,3-d]pyrimidin-7(8H... |
Application: | Potent, selective PAK1 inhibitor |
CAS | 1432908-05-8 |
MW: | 518.1 D |
From 64.00€
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Item number: Cay21469-5
G-5555 is an inhibitor of p21-activated kinase 1 (PAK1, Ki = 3.7 nM), a non-receptor serine/threonine kinase involved in tumorigenesis. It is selective for PAK1 over the majority of targets in a panel of 235 kinases but does inhibit PAK2, PAK3, KHS1, LCK, MST3, MST4, SIK2, and YSK1 by greater than 70% with IC50...
Keywords: | 8-[(trans-5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methyl-2-pyridinyl)phenyl]-2-(methylamino)-pyrido[2,3-d]pyrimid... |
Application: | PAK1 Inhibitor |
CAS | 1648863-90-4 |
MW: | 493 D |
From 60.00€
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Item number: ARG51653.100
Protein function: Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes. Can directly...
Keywords: | Anti-phospho-PAK1, Anti-phospho-PAK-1, Anti-phospho-p65-PAK, Anti-phospho-Alpha-PAK, EC=2.7.11.1,... |
Application: | ICC, IF, IHC (paraffin), WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 436.00€
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Item number: ARG64016.100
Protein function: Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes. Can directly...
Keywords: | Anti-PAK1, Anti-PAK-1, Anti-p65-PAK, Anti-Alpha-PAK, EC=2.7.11.1, Anti-p21-activated kinase 1,... |
Application: | ELISA, WB |
Host: | Goat |
Species reactivity: | human, mouse, rat |
784.00€
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Item number: A301-260A
Protein function: Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes. Can directly...
Keywords: | Anti-PAK1, Anti-PAK-1, Anti-p65-PAK, Anti-Alpha-PAK, EC=2.7.11.1, Anti-p21-activated kinase 1,... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: BPS-40072
Active human PAK1 (GenBank Accession No. NM_002576.4), amino acids 248- 545, MW=33.6 kDa, expressed in E. coli.
Keywords: | PAK-1, p65-PAK, Alpha-PAK, p21-activated kinase 1, Serine/threonine-protein kinase PAK 1, |
Application: | Enzyme kinetics, inhibitor screening |
MW: | 33.6 kD |
1,080.00€
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Item number: 600-401-413
Protein function: Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes. Can directly...
Keywords: | Anti-phospho-PAK1, Anti-phospho-PAK-1, Anti-phospho-p65-PAK, Anti-phospho-Alpha-PAK, EC=2.7.11.1,... |
Application: | ELISA, WB |
Host: | Rabbit |
Species reactivity: | human |
684.00€
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Item number: 612-401-E05
Anti-PAK 1/2/3 pT402 antibody is directed against rat PAK protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification and is specific for the phosphorylated protein. The immunolabeling of PAK is completely eliminated by ?-phosphatase treatment. Reactivity is expected from...
Keywords: | Anti-phospho-Pak1, Anti-phospho-PAK-1, Anti-phospho-p68-PAK, Anti-phospho-Alpha-PAK, EC=2.7.11.1, Anti-phospho-Protein... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | rat |
684.00€
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Item number: NSJ-R30640
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Serine/threonine-protein kinase PAK 1 is an enzyme that in humans is encoded by the PAK1 gene. PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activated...
Keywords: | Anti-PAK1, Anti-PAK-1, Anti-p65-PAK, Anti-Alpha-PAK, EC=2.7.11.1, Anti-p21-activated kinase 1,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
755.00€
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