176 products were found matching "K04398"!

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Caspase 8 is also known as CAP4, MACH or MCH5. The CASP8 gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive...

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of...

A fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety.

This kits makes use of a cell-permeant green fluorecent probe (FAM-LETD-FMK ) that binds to active caspase-8 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.

A peptide inhibitor of caspase-8, inhibits TNF-alpha-induced apoptosis in isolated human neutrophils at 3 or 10 µM, decreases HRV replication and HRV-induced apoptosis in HeLa cells at 100 µM, reduces tumor growth and increases tumor macrophage and T cell infiltration in a mouse model of NMU-induced lung cancer when...

Our Cell Meter(TM) assay kits are a set of tools for monitoring cellular functions. There are a variety of parameters that can be used to monitor cell apoptosis. This particular kit is designed to monitor cell apoptosis by measuring caspase 8 activity. Caspase 8 is a caspase protein, encoded by the CASP8 gene....

A fluorogenic substrate for caspase-8, AMC is released upon enzymatic cleavage by caspase-8 and its fluorescence can be used to quantify caspase-8 activity, ex/em = 340-360/440-460 nm, respectively. Formulation: A solid. InChI:...

Caspase-8 is an initiator caspase with roles in cell death, including induction of apoptosis and pyroptosis and inhibition of necroptosis. It is widely expressed during development and adulthood with high levels of expression in the heart and limb buds, as well as other tissues, in development and in leukocytes in...

Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm.This R110 substrate is specific for caspases 3 and 7.

Recognizes the p18 subunit of human caspase-8. Liquid. Purified from concentrated hybridoma tissue culture supernatant. Procaspase-8 belongs to the family of caspases. Binding of FasL to Fas leads to formation of a receptor complex at the cellular membrane, which was named DISC. The DISC consists of oligomerized...

A fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety.

Detect caspase-8 activity with the SR-FLICAT Caspase-8 Assay Kit. This in vitro assay employs the fluorescent inhibitor probe SR-LETD-FMK to label active caspase-8 enzymes in living cells or tissue samples. Analyze the fluorescent signal using fluorescence microscopy, a fluorescent plate reader, or by flow cytometry.