169 products were found matching "K04398"!

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Caspase 8 is also known as CAP4, MACH or MCH5. The CASP8 gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive...

A fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety.

This kits makes use of a cell-permeant green fluorecent probe (FAM-LETD-FMK ) that binds to active caspase-8 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.

Our Cell Meter(TM) assay kits are a set of tools for monitoring cellular functions. There are a variety of parameters that can be used to monitor cell apoptosis. This particular kit is designed to monitor cell apoptosis by measuring caspase 8 activity. Caspase 8 is a caspase protein, encoded by the CASP8 gene....

A peptide inhibitor of caspase-8, inhibits TNF-alpha-induced apoptosis in isolated human neutrophils at 3 or 10 µM, decreases HRV replication and HRV-induced apoptosis in HeLa cells at 100 µM, reduces tumor growth and increases tumor macrophage and T cell infiltration in a mouse model of NMU-induced lung cancer when...

Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm.This R110 substrate is specific for caspases 3 and 7.

Recognizes the p18 subunit of human caspase-8. Liquid. Purified from concentrated hybridoma tissue culture supernatant. Procaspase-8 belongs to the family of caspases. Binding of FasL to Fas leads to formation of a receptor complex at the cellular membrane, which was named DISC. The DISC consists of oligomerized...

A fluorogenic substrate for caspase-8, AMC is released upon enzymatic cleavage by caspase-8 and its fluorescence can be used to quantify caspase-8 activity, ex/em = 340-360/440-460 nm, respectively. Formulation: A solid. InChI:...

A fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety.

Detect caspase-8 activity with the SR-FLICAT Caspase-8 Assay Kit. This in vitro assay employs the fluorescent inhibitor probe SR-LETD-FMK to label active caspase-8 enzymes in living cells or tissue samples. Analyze the fluorescent signal using fluorescence microscopy, a fluorescent plate reader, or by flow cytometry.

Ac-LETD-AFC is a fluorogenic substrate that can be cleaved specifically by caspase-8. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.Formal Name:...