77 products were found matching "K04396"!

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two...

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. CASP6 antibody detects caspase 6, a cysteine protease encoded by the CASP6 gene. Alternate identifiers include MCH2 and apoptotic cysteine protease 6. Caspase 6 belongs to the caspase family of...

This kits makes use of a cell-permeant green fluorecent probe (FAM-VEID-FMK ) that binds to active caspase-6 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.

Ac-VEID-AMC is a fluorogenic substrate based on the caspase-6 cleavage site in lamin A at amino acids VEID during apoptosis. It has also been reported to be cleaved by related proteases, including caspase-8. Caspase activity can be quantified by fluorescent detection of free AMC (also known as...

Ac-VEID-CHO is an inhibitor of caspase-6 (IC50 = 16.2 nM). It is selective for caspase-6 over caspase-7 (IC50 = 162.1 nM) but can also inhibit caspase-3 (IC50 = 13.6 nM). Ac-VEID-CHO (100 µM) inhibits ricin-induced caspase-6-, but not caspase-3-, like activity in U937 cells. It also inhibits caspase-6-like activity...

Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. [The UniProt Consortium]

The Homogeneous Caspase-6 Assay Kit is a complete assay system designed to measure Caspase-6 activity for screening and profiling applications. It comes in a convenient 96-well format, with all the reagents necessary for 100 fluorescent Caspase-6 activity measurements. In addition, the kit includes purified...

This kits makes use of a cell-permeant green fluorecent probe (FAM-VEID-FMK ) that binds to active caspase-6 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.

Anti-Caspase-6 Antibody is immunoaffinity purified. Depending on cell lines or tissues used, either full-length or other cleavage products may be observed. Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as...

Anti-Caspase-6 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Depending on cell lines or tissues used, either full-length or other cleavage products may be observed. Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution....

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Caspase-6 is an enzyme that in humans is encoded by the CASP6 gene. This gene encodes a protein that is a member of the cysteine-aspartic acid protease family. Using radiation hybrid mapping, the CASP6 gene was localized to human chromosome 4q25-q26. It...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Caspase 6 is an enzyme that in humans is encoded by the CASP6 gene. This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Using radiation hybrid mapping, the CASP6 gene is localized to human chromosome 4q25-q26. It...