72 products were found matching "K04396"!

Molecular weight: 871.93. Extinction coefficient (cm^-1 M^-1): 18000. Excitation (nm): 362. Emission (nm): 499. Z-IETD-aminoluciferin is a luminogenic substrate that measures caspase-6 and granzyme B activities in apoptotic cells. Caspases, a family of aspartate-specific cysteine proteases, are key regulators of...

Molecular weight: 869.96. Extinction coefficient (cm^-1 M^-1): 18000. Excitation (nm): 362. Emission (nm): 499. Z-VEID-aminoluciferin is a luminogenic substrate that measures caspase-6 activity in apoptotic cells. Caspases, a family of aspartate-specific cysteine proteases, are key regulators of apoptosis,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CASP6. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CASP6. Next,...

This kits makes use of a cell-permeant green fluorecent probe (FAM-VEID-FMK ) that binds to active caspase-6 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.

Ac-VEID-AMC is a fluorogenic substrate based on the caspase-6 cleavage site in lamin A at amino acids VEID during apoptosis. It has also been reported to be cleaved by related proteases, including caspase-8. Caspase activity can be quantified by fluorescent detection of free AMC (also known as...

Ac-VEID-CHO is an inhibitor of caspase-6 (IC50 = 16.2 nM). It is selective for caspase-6 over caspase-7 (IC50 = 162.1 nM) but can also inhibit caspase-3 (IC50 = 13.6 nM). Ac-VEID-CHO (100 µM) inhibits ricin-induced caspase-6-, but not caspase-3-, like activity in U937 cells. It also inhibits caspase-6-like activity...

Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. [The UniProt Consortium]

The Homogeneous Caspase-6 Assay Kit is a complete assay system designed to measure Caspase-6 activity for screening and profiling applications. It comes in a convenient 96-well format, with all the reagents necessary for 100 fluorescent Caspase-6 activity measurements. In addition, the kit includes purified...

This kits makes use of a cell-permeant green fluorecent probe (FAM-VEID-FMK ) that binds to active caspase-6 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.

Anti-Caspase-6 Antibody is immunoaffinity purified. Depending on cell lines or tissues used, either full-length or other cleavage products may be observed. Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as...

Anti-Caspase-6 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Depending on cell lines or tissues used, either full-length or other cleavage products may be observed. Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution....

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Caspase-6 is an enzyme that in humans is encoded by the CASP6 gene. This gene encodes a protein that is a member of the cysteine-aspartic acid protease family. Using radiation hybrid mapping, the CASP6 gene was localized to human chromosome 4q25-q26. It...