61 products were found matching "K04392"!

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Anti-Active Rac-GTP, monoclonal
Anti-Active Rac-GTP, monoclonal

Item number: NB-26903

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the...
Keywords: Anti-MIG5, Anti-RAC1, Anti-TC25, Anti-p21-Rac1, Anti-Ras-like protein TC25, Anti-Cell migration-inducing gene 5 protein,...
Application: IP, IHC
Host: Mouse
Species reactivity: vertebrates
717.00€ *
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Rat Rac1 (Ras Related C3 Botulinum Toxin Substrate 1) ELISA Kit
Rat Rac1 (Ras Related C3 Botulinum Toxin Substrate 1)...

Item number: ELK-ELK7967.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat Rac1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat Rac1. Next,...
Keywords: p21-Rac1, Ras-related C3 botulinum toxin substrate 1
Application: ELISA
Species reactivity: rat
365.00€ * From 328.50€ *
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Human Rac1 (Ras Related C3 Botulinum Toxin Substrate 1) ELISA Kit
Human Rac1 (Ras Related C3 Botulinum Toxin Substrate 1)...

Item number: ELK-ELK7041.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human Rac1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human Rac1. Next,...
Keywords: MIG5, TC25, p21-Rac1, Ras-like protein TC25, Cell migration-inducing gene 5 protein, Ras-related C3 botulinum toxin...
Application: ELISA
Species reactivity: human
365.00€ * From 328.50€ *
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NSC 23766 (hydrochloride)
NSC 23766 (hydrochloride)

Item number: Cay13196-1

Rac1 is a GTPase that is involved in the regulation of the cell cycle, cell-cell adhesion, motility, and differentiation. Rac1 is activated by its interaction with specific guanine nucleotide exchange factors (GEFs). NSC 23766 is a cell-permeable, reversible inhibitor of Rac1 activation by the Rac-specific GEFs...
Keywords: N6-[2-[[4-(diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine, trihydrochloride
Application: Rac1 inhibitor
CAS 1177865-17-6
MW: 531 D
From 44.00€ *
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EHT 1864
EHT 1864

Item number: Cay17258-1

EHT 1864 is an inhibitor of the Rac subfamily of Rho GTPases, that binds to Rac1, Rac1b, Rac2, and Rac3 with Kd values of 40, 50, 50, and 250 nM, respectively. It can reverse transformation of NIH 3T3 fibroblasts caused by constitutively activated Rac1, as well as Rac-dependent transformation caused by Tiam1 or Ras....
Keywords: 2-(4-morpholinylmethyl)-5-[[5-[[7-(trifluoromethyl)-4-quinolinyl]thio]pentyl]oxy]-4H-pyran-4-one, dihydrochloride
Application: Rac inhibitor
CAS 754240-09-0
MW: 581.5 D
From 43.00€ *
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Anti-Rac1
Anti-Rac1

Item number: NB-21003

Concentration: 0.2 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity...
Keywords: Anti-MIG5, Anti-RAC1, Anti-TC25, Anti-p21-Rac1, Anti-Ras-like protein TC25, Anti-Cell migration-inducing gene 5 protein,...
Application: ELISA, WB
Host: Rabbit
Species reactivity: vertebrates
317.00€ *
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EHop-016
EHop-016

Item number: Cay21557-10

EHop-016 is an inhibitor of the small Rho GTPases Rac1 and Rac3. It inhibits Rac1 activity in MDA-MB-435 breast cancer cells with an IC50 value of 1.1 µM in a Rac1 activation assay. At a concentration of 1 µM, EHop-016 inhibits 58% of Rac3 activity, and it inhibits Cdc42 activity but only at higher concentrations...
Keywords: N4-(9-ethyl-9H-carbazol-3-yl)-N2-[3-(4-morpholinyl)propyl]-2,4-pyrimidinediamine
Application: RAC1 / RAC3 inhibitor
CAS 1380432-32-5
MW: 430.6 D
From 66.00€ *
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ML-099
ML-099

Item number: Cay15176-1

ML-099 is a small molecule pan activator of Ras-related GTPases, activating Rac1, cell division cycle 42, Ras, and Rab-2A with EC50 values of 20, 100, 141, and 355 nM, respectively.Formal Name: 2-[(2-phenylethyl)thio]-3-pyridinecarboxylic acid. CAS Number: 496775-95-2. Synonyms: CID-888706. Molecular Formula:...
Keywords: CID-888706, 2-[(2-phenylethyl)thio]-3-pyridinecarboxylic acid
Application: Ras-related GTPase activator
CAS 496775-95-2
MW: 259.3 D
From 50.00€ *
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Plitidepsin
Plitidepsin

Item number: Cay34053-500

Plitidepsin is a depsipeptide that was originally isolated from Aplidium albicans and has diverse biological activities. It binds to the alpha subunit isoform eEF1A2 of eukaryotic elongation factor 1 (eEF1, Kd = 79 nM) and inhibits the proliferation of NCI H460 non-small cell lung cancer (NSCLC) and HGC-27 gastric...
Keywords: Aplidin, Dehydrodidemnin B, N-[1-(1,2-dioxopropyl)-L-prolyl]-didemnin A
Application: Bioactive depsipeptide, antineoplastic
CAS 137219-37-5
MW: 1110.3 D
From 310.00€ *
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Anti-phospho-Rac1 (Ser71)
Anti-phospho-Rac1 (Ser71)

Item number: ARG51695.100

Protein function: Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and...
Keywords: Anti-phospho-RAC1, Anti-phospho-MIG5, Anti-phospho-TC25, Anti-phospho-p21-Rac1, Anti-phospho-Ras-like protein TC25,...
Application: WB
Host: Rabbit
Species reactivity: human, mouse, rat
From 436.00€ *
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Anti-Rac1, clone 1301CT276.121.104
Anti-Rac1, clone 1301CT276.121.104

Item number: ARG54719.100

Protein function: Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and...
Keywords: Anti-RAC1, Anti-MIG5, Anti-TC25, Anti-p21-Rac1, Anti-Ras-like protein TC25, Anti-Cell migration-inducing gene 5 protein,...
Application: FC, IHC, WB
Host: Mouse
Species reactivity: human, mouse, rat
584.00€ *
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Anti-RAC1
Anti-RAC1

Item number: NSJ-R32162

0.5mg/ml if reconstituted with 0.2ml sterile DI water. RAC1, also known as Ras-related C3 botulinum toxin substrate 1, is a protein found in human cells. It is encoded by the RAC1 gene. This gene can produce a variety of alternatively splicedversions of the Rac1 protein, which appear to carry out different...
Keywords: Anti-RAC1, Anti-TC25, Anti-MIG5, Anti-p21-Rac1, Anti-Ras-like protein TC25, Anti-Cell migration-inducing gene 5 protein,...
Application: WB
Host: Rabbit
Species reactivity: human, mouse, rat
755.00€ *
Review
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