- Search results for K04388
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75 products were found matching "K04388"!
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Item number: ELK-ELK6823.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse TGFbR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse TGFbR2....
Keywords: | TGFR-2, Tgfbr2, TbetaR-II, EC=2.7.11.30, TGF-beta receptor type-2, TGF-beta type II receptor, TGF-beta receptor type II,... |
Application: | ELISA |
Species reactivity: | mouse |
From 365.00€
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Item number: ELK-ELK3210.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TGFbR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TGFbR2....
Keywords: | TGFR-2, TGFBR2, TbetaR-II, EC=2.7.11.30, TGF-beta receptor type-2, TGF-beta type II receptor, TGF-beta receptor type II,... |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
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Item number: ELK-ELK7556.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat TGFbR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TGFbR2. Next,...
Keywords: | TGFR-2, Tgfbr2, TbetaR-II, EC=2.7.11.30, TGF-beta receptor type-2, TGF-beta type II receptor, TGF-beta receptor type II,... |
Application: | ELISA |
Species reactivity: | rat |
From 365.00€
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Item number: Cay15409-1
LY2157299 is a small molecule inhibitor of the TGF-beta receptor type 1/type II kinases (IC50 = 69 nM). It has been used to study the role of TGF-beta signaling in tumor cell migration and metastasis in pancreatic tumor cell lines where 5 µM of the compound completely disrupts Smad-2 phosphorylation, an immediate...
Keywords: | 4-[5,6-dihydro-2-(2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2-(4-morpholinyl)ethoxy]-quinoline |
Application: | TGFBR1/2 inhibitor |
CAS | 700874-71-1 |
MW: | 441.5 D |
From 60.00€
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Item number: NSJ-R32086
0.5mg/ml if reconstituted with 0.2ml sterile DI water. TGFBR2 (Transforming growth factor, beta receptor II) is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein,...
Keywords: | Anti-TGFR-2, Anti-TGFBR2, Anti-TbetaR-II, EC=2.7.11.30, Anti-TGF-beta receptor type-2, Anti-TGF-beta type II receptor,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
755.00€
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Item number: NSJ-F45533-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators....
Keywords: | Anti-Tgfbr2, Anti-TGFR-2, Anti-TbetaR-II, EC=2.7.11.30, Anti-TGF-beta receptor type-2, Anti-TGF-beta receptor type II,... |
Application: | WB, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 326.00€
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Item number: Cay23326-10
ITD 1 is an inhibitor of TGF-beta (IC50 = 0.85 µM). It is selective for TGF-beta in an SBE4/Smad reporter assay, providing 83% inhibition when used at a concentration of 2.5 µM, over activin A, which is inhibited by 51% when used at the same concentration. ITD 1 inhibits TGF-beta signaling by induction of TGF-beta...
Keywords: | 4-[1,1'-biphenyl]-4-yl-1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-5-oxo-3-quinolinecarboxylic acid, ethyl ester |
Application: | TGF-beta inhibitor, TGF-beta receptor type II degradation inducer |
CAS | 1099644-42-4 |
MW: | 415.5 D |
From 125.00€
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Item number: A304-413A
Protein function: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus...
Keywords: | Anti-TGFR-2, Anti-TGFBR2, Anti-TbetaR-II, EC=2.7.11.30, Anti-TGF-beta receptor type-2, Anti-TGF-beta receptor type II,... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A304-414A
Protein function: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus...
Keywords: | Anti-TGFR-2, Anti-TGFBR2, Anti-TbetaR-II, EC=2.7.11.30, Anti-TGF-beta receptor type-2, Anti-TGF-beta receptor type II,... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: BPS-40707
Human transforming growth factor beta receptor 2 (TGFbetaR2). GenBank Accession No. NM_003242 (var2), a.a. 190-567 (end), with N-terminal GST-tag, MW=69.9 kDa, expressed in an Sf9 cell expression system.
Keywords: | TGFBR2, TGFR-2, TbetaR-II, EC=2.7.11.30, TGF-beta receptor type-2, TGF-beta type II receptor, TGF-beta receptor type II,... |
Application: | Studying protein binding, receptor activity, screening small molecules |
Expressed in: | insect cells |
Origin: | human |
MW: | 69.9 kD |
613.00€
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Item number: NSJ-R30965
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Transforming growth factor, beta receptor II, also known as TGFBR2 and TGFR-2, is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. A TGFBR2 cDNA encoding a deduced 565-amino acid protein with a calculated molecular mass of...
Keywords: | Anti-TGFBR2, Anti-TGFR-2, Anti-TbetaR-II, EC=2.7.11.30, Anti-TGF-beta receptor type-2, Anti-TGF-beta receptor type II,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
755.00€
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Item number: E-AB-33088.120
TGFBR2 (Transforming Growth Factor Beta Receptor 2) is a Protein Coding gene. Diseases associated with TGFBR2 include Loeys-Dietz Syndrome 2 and Esophageal Cancer. Among its related pathways are SMAD2/3 MH2 Domain Mutants in Cancer and Extracellular vesicle-mediated signaling in recipient cells. GO annotations...
Keywords: | Anti-TGFR-2, Anti-TGFBR2, Anti-TbetaR-II, EC=2.7.11.30, Anti-TGF-beta receptor type-2, Anti-TGF-beta receptor type II,... |
Application: | WB, IHC (paraffin), ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 71.00€
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