- Search results for K04365
Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
193 products were found matching "K04365"!
Close filters
Filter by:
No results were found for the filter!
Item number: NSJ-RQ5438
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The BRAF gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion....
Keywords: | Anti-p94, Anti-BRAF1, Anti-Proto-oncogene B-Raf, Anti-Serine/threonine-protein kinase B-raf, Anti-v-Raf murine sarcoma... |
Application: | IHC (paraffin), WB |
Host: | Rabbit |
Species reactivity: | human |
755.00€
*
Item number: NSJ-RQ5439
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The BRAF gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion....
Keywords: | Anti-phospho-p94, Anti-phospho-BRAF1, Anti-phospho-Proto-oncogene B-Raf, Anti-phospho-Serine/threonine-protein kinase... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
755.00€
*
Item number: Cay37580-1
AZ 304 is an inhibitor of B-RAF and B-RAF containing a valine-to-glutamate substitution at position 600 (B-RAFV600E, IC50s= 79 and 38 nM, respectively). It is selective for B-RAF and B-RAFV600E over MAP3K7 and C-terminal Src kinase (CSK) (IC50s = 6,400 and 7,050 nM, respectively), as well as insulin-like growth...
Keywords: | 3-(1-cyano-1-methylethyl)-N-[3-[(7-methoxy-4-quinazolinyl)amino]-4-methylphenyl]-benzamide |
Application: | B-RAF / B-RAFV600E inhibitor |
CAS | 942507-42-8 |
MW: | 451.5 D |
From 48.00€
*
Item number: ELK-ELK4445.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human BRAF. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human BRAF. Next,...
Keywords: | p94, BRAF1, Proto-oncogene B-Raf, Serine/threonine-protein kinase B-raf, v-Raf murine sarcoma viral oncogene homolog B1 |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
*
Item number: LC-V-2800_10g
Soluble in DMSO at 100 mg/mL, very poorly soluble in ethanol, very poorly soluble in water, maximum solubility in plain water is estimated to be about 25-50 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
Keywords: | RG-7204, Ro 51-85426, Vemurafenib,... |
Application: | B-Raf kinase (mutant V600E and wild type) inhibitor |
CAS | 918504-65-1 |
MW: | 489,92 D |
From 88.00€
*
Item number: NB-26039
Concentration: 0.5 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. B-Raf is a member of the Raf family of Ser/Thr protein kinases. It functions downstream of Ras to regulate the MAP kinase signaling pathway. Mutations in the BRAF gene cause diseases. Inherited mutations in...
Keywords: | Anti-p94, Anti-BRAF, Anti-BRAF1, EC=2.7.11.1, Anti-Proto-oncogene B-Raf, Anti-Serine/threonine-protein kinase B-raf,... |
Application: | ELISA, WB, IHC, IP |
Host: | Mouse |
717.00€
*
Item number: Cay10618-5
PLX4032 is an orally bioavailable, ATP-competitive inhibitor of mutant V600E and wild type B-Raf kinases (IC50s = 31 and 100 nM, respectively). It inhibits cell proliferation in a variety of cell lines expressing B-Raf V600E and synergizes strongly with taxol, vinblastine, and oxaliplatin in inhibiting the...
Keywords: | RG-7204, Ro 51-85426, Vemurafenib,... |
Application: | B-Raf kinase (mutant V600E and wild type) inhibitor |
CAS | 918504-65-1 |
MW: | 489.9 D |
From 60.00€
*
Item number: BPS-40533
Human v-raf murine sarcoma viral oncogene homolog B1 (BRAF), GenBank Accession No. NM_004333, a.a. 417-end with Val-to-Glu mutation on a.a. 600 and N-terminal GST tag, MW=69 kDa, expressed in Sf9 insect cells via a baculovirus expression system. This mutation is often cited as V599E.
Keywords: | p94, BRAF1, Proto-oncogene B-Raf, Serine/threonine-protein kinase B-raf, v-Raf murine sarcoma viral oncogene homolog B1, |
Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Expressed in: | Insect cells |
Origin: | human |
MW: | 69 kD |
525.00€
*
Item number: Cay16989-5
Dabrafenib is an ATP-competitive inhibitor of Raf kinases (IC50s = 0.64, 0.68, and 5 nM for wild-type B-RAF kinase, mutant B-RAFV600E, and wild-type C-RAF kinase, respectively). It also inhibits the tyrosine kinase-like kinases ALK5 and LIMK1 (IC50s = 11 and 15 nM, respectively) and the calcium/calmodulin-dependent...
Keywords: | GSK2118436,... |
Application: | B-Raf V600E inhibitor |
CAS | 1195765-45-7 |
MW: | 519.6 D |
From 48.00€
*
Item number: Cay15142-1
The Raf kinases activate cellular pathways that lead to cell proliferation and can contribute to certain types of cancer. Mutations in the kinase B-Raf are involved in a wide range of cancers. In particular, the mutation B-RafV600E occurs in melanomas and thyroid cancer but is poorly targeted by many inhibitors of...
Keywords: | Raf Kinase Inhibitor V, N-[3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide |
Application: | BRAFV600E inhibitor |
CAS | 918505-84-7 |
MW: | 413.8 D |
From 60.00€
*
Item number: A301-695A
Protein function: Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway. [The UniProt Consortium]
Keywords: | Anti-p94, Anti-BRAF, Anti-BRAF1, EC=2.7.11.1, Anti-Proto-oncogene B-Raf, Anti-Serine/threonine-protein kinase B-raf,... |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
*
Item number: NB-26110
Concentration: 0.5 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. B-Raf is a member of the Raf family of Ser/Thr protein kinases. It functions downstream of Ras to regulate the MAP kinase signaling pathway. Mutations in the BRAF gene cause diseases. Inherited mutations in...
Keywords: | Anti-p94, Anti-BRAF, Anti-BRAF1, EC=2.7.11.1, Anti-Proto-oncogene B-Raf, Anti-Serine/threonine-protein kinase B-raf,... |
Application: | ELISA, WB, IHC, IF |
Host: | Mouse |
717.00€
*