- Search results for K04306
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18 products were found matching "K04306"!
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Item number: Cay40956-1
AZD 5462 is an agonist of relaxin family peptide receptor 1 (RXFP1). It induces cAMP mobilization in HEK293 cells expressing the human RXFP1 (EC50 = 15.85 nM). AZD 5462 increases heart rate and mean arterial blood pressure (MABP) in rats. It increases left ventricular ejection fraction (LVEF) in a cynomolgus monkey...
Keywords: | cis-4-[2-fluoro-4-methoxy-5-[[[(1S,2R,3S,4R)-3-[[[(1-methylcyclobutyl)methyl]amino]carbonyl]bicyclo[2.2.1]hept-2-yl]amino]... |
Application: | RXFP1 agonist |
CAS | 2787501-83-9 |
MW: | 544.7 D |
From 177.00€
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Item number: Cay21134-1
ML-290 is an allosteric agonist of relaxin family peptide receptor 1 (RXFP1, EC50 = 0.094 µM for the human receptor in a cAMP produciton assay). It is selective for RXFP1 over RXFP2 (EC50 = 1.5 µM). ML-90 (250 nM) induces expression of VEGF in THP-1 cells expressing human RXFP1. It stimulates cAMP release from...
Keywords: | RXFP1 Agonist 8, 2-[[2-(1-methylethoxy)benzoyl]amino]-N-[3-[(trifluoromethyl)sulfonyl]phenyl]-benzamide |
Application: | RXFP1 agonist |
CAS | 1482500-76-4 |
MW: | 506.5 D |
From 52.00€
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Item number: G-HUFI02831.96
Application: | ELISA |
Species reactivity: | human |
641.00€
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Item number: ATA-HPA027067.100
Protein function: Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. [The UniProt...
Keywords: | Anti-LGR7, Anti-RXFP1, Anti-Relaxin receptor 1, Anti-Relaxin family peptide receptor 1, Anti-Leucine-rich... |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 300.00€
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NEW
Item number: CSB-CL875715HU.10
Length: 2274 Sequence: atgacatctg gttctgtctt cttctacatc ttaatttttg gaaaatattt ttctcatggg ggtggacagg atgtcaagtg ctcccttggc tatttcccct gtgggaacat cacaaagtgc ttgcctcagc tcctgcactg taacggtgtg gacgactgcg ggaatcaggc cgatgaggac aactgtggag acaacaatgg atggtctctg caatttgaca aatattttgc cagttactac aaaatgactt cccaatatcc...
Keywords: | LGR7, RXFP1, Relaxin receptor 1, Relaxin family peptide receptor 1, Leucine-rich repeat-containing G-protein coupled... |
Application: | Molecular biology, clone |
Species reactivity: | human |
467.00€
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Item number: DIM-FLP100458.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
Keywords: | LGR7, RXFP1, Relaxin receptor 1, Relaxin family peptide receptor 1, Leucine-rich repeat-containing G-protein coupled... |
Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
Expressed in: | Human cells |
Origin: | human |
MW: | 87 kD |
From 1,260.00€
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Item number: E-AB-92757.120
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a...
Keywords: | LGR7, RXFP1, Relaxin receptor 1, Relaxin family peptide receptor 1, Leucine-rich repeat-containing G-protein coupled... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 198.00€
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Item number: ELK-ES11633.100
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a...
Keywords: | Anti-LGR7, Anti-RXFP1, Anti-Relaxin receptor 1, Anti-Relaxin family peptide receptor 1, Anti-Leucine-rich... |
Application: | WB, ELISA |
Host: | Rabbit |
Species reactivity: | human, rat, mouse |
From 169.00€
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Item number: VHPS-5280
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | LGR7, RXFP1, Relaxin receptor 1, Relaxin family peptide receptor 1, Leucine-rich repeat-containing G-protein coupled... |
Application: | RNA quantification |
43.00€
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Item number: VMPS-3488
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | Rxfp1, Gm1018, Relaxin receptor 1, Relaxin family peptide receptor 1, Leucine-rich repeat-containing G-protein coupled... |
Application: | RNA quantification |
43.00€
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Item number: 041344-APC.200
Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. Applications: Suitable for use in...
Keywords: | Anti-LGR7, Anti-RXFP1, Anti-Relaxin receptor 1, Anti-Relaxin family peptide receptor 1, Anti-Leucine-rich... |
Application: | FLISA, WB |
Host: | Rabbit |
Species reactivity: | human |
993.00€
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Item number: 041344-Biotin.200
Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. Applications: Suitable for use in...
Keywords: | Anti-LGR7, Anti-RXFP1, Anti-Relaxin receptor 1, Anti-Relaxin family peptide receptor 1, Anti-Leucine-rich... |
Application: | ELISA, WB |
Host: | Rabbit |
Species reactivity: | human |
993.00€
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