- Search results for K04270
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25 products were found matching "K04270"!
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Item number: ELK-ELK4783.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human P2RY1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human P2RY1. Next,...
Keywords: | P2Y1, P2RY1, ADP receptor, P2Y purinoceptor 1, Purinergic receptor |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
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Item number: Cay21230-10
2-Methylthioadenosine diphosphate (2-MeSADP) is an agonist of purinergic P2Y receptors with EC50s of 5.13 and 0.89 nM for human recombinant P2Y1 and P2Y12 receptors, respectively. It also acts as an agonist at rat P2Y1 and P2Y12 and mouse P2Y13 receptors (EC50s = 0.58, 0.89, and 6.2 nM, respectively). It induces...
Keywords: | 2-MeSADP, 2-Methylthio-ADP, 2-(methylthio)-adenosine 5'-(trihydrogen diphosphate), trisodium salt |
Application: | P2RY1 / P2RY12 / P2Y13 agonist |
CAS | 475193-31-8 |
MW: | 539.2 D |
From 77.00€
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Item number: Cay38535-2.6
Rp-Adenosine-5'-O-(1-thiotriphosphate) (Rp-ATP-alpha-S) is an isomer of the sulfur-containing nucleotide derivative ATP-alpha-S and an agonist of the purinergic P2Y1 receptor. It increases calcium mobilization in HEK293 cells expressing the human P2Y1 receptor (EC50 = 75 nM). Rp-ATP-alpha-S binds to washed isolated...
Keywords: | Rp-ATP-alpha-S, Adenosine, 5'->P''-ester with [P''(R)]-thiotriphosphoric acid ((HO)2P(O)OP(O)(OH)OP(O)(OH)(SH)),... |
Application: | ATP-alpha-S isomer, P2Y1 receptor agonist |
MW: | 611.2 D |
321.00€
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Item number: Cay38536-2.6
Sp-Adenosine-5'-O-(1-thiotriphosphate) (Sp-ATP-alpha-S) is an isomer of the sulfur-containing nucleotide derivative ATP-alpha-S and an agonist of the purinergic P2Y1 receptor. It increases calcium mobilization in HEK293 cells expressing the P2Y1 receptor (EC50 = 9.4 nM for the human receptor). Sp-ATP-alpha-S...
Keywords: | Sp-ATP-alpha-S, adenosine, 5'->P''-ester with (P''S)-thiotriphosphoric acid ((HO)2P(O)OP(O)(OH)OP(O)(OH)(SH)), tetrasodium... |
Application: | ATP-alpha-S isomer, P2Y1 receptor agonist |
MW: | 611.2 D |
308.00€
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Item number: Cay10011450-10
MRS2179 is a competitive purinergic P2Y1 receptor antagonist (Kb = 102 nM). It is selective for P2Y1 over P2Y2, P2Y4, P2Y6, P2Y12, and P2Y13, as well as P2X1-4, receptors at 10 µM. MRS2179 reduces phospholipase C (PLC) activity induced by the P2Y receptor agonist 2-methylthioadenosine diphosphate (2-MeSADP,...
Keywords: | 2'-deoxy-N-methyl-3'-adenylic acid, 5'-(dihydrogen phosphate), ammonium salt, hydrate |
Application: | Competitive P2Y1 receptor antagonist |
MW: | 425.2 D |
From 54.00€
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Item number: Cay29444-10
BPTU is an allosteric antagonist of the purinergic P2Y1 receptor (Ki = 6 nM for the human receptor). BPTU is selective for P2Y1 over P2Y2, P2Y6, P2Y11, P2Y12, and P2Y14 receptors (Kis = >3,500 nM). It inhibits platelet aggregation in human platelet-rich plasma (hPRP, IC50 = 2.1 µM). BPTU reduces thrombus weight by...
Keywords: | N-[2-[2-(1,1-dimethylethyl)phenoxy]-3-pyridinyl]-N'-[4-(trifluoromethoxy)phenyl]-urea |
Application: | Allosteric P2Y1 receptor antagonist |
CAS | 870544-59-5 |
MW: | 445.4 D |
From 43.00€
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Item number: ARG57509.100
Protein function: Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [The UniProt Consortium]
Keywords: | Anti-P2Y1, Anti-P2RY1, Anti-ATP receptor, Anti-P2Y purinoceptor 1, Anti-Purinergic receptor |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
584.00€
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Item number: E-AB-12606.120
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In...
Keywords: | Anti-P2Y1, Anti-P2RY1, Anti-ATP receptor, Anti-P2Y purinoceptor 1, Anti-Purinergic receptor, P2RY1 Polyclonal Antibody |
Application: | IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 71.00€
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Item number: G-HUFI03143.96
Protein function: Receptor for extracellular adenine nucleotides such as ADP (PubMed:9442040, PubMed:9038354, PubMed:25822790). In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation...
Keywords: | P2Y1, P2RY1, ADP receptor, P2Y purinoceptor 1, Purinergic receptor |
641.00€
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Item number: Cay28437-5
LUF6000 is a positive allosteric modulator of adenosine A3 receptors. It reduces dissociation of the agonist I-AB-MECA from A3 receptors and increases the efficacy, but not potency, of 2-Cl-IB-MECA-induced inhibition of forskolin-stimulated cAMP accumulation by 45% in CHO cells expressing the human receptor when...
Keywords: | 2-cyclohexyl-N-(3,4-dichlorophenyl)-3H-imidazo[4,5-c]quinolin-4-amine |
Application: | Adenosine receptor A3 agonist |
CAS | 890087-21-5 |
MW: | 411.3 D |
From 109.00€
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Item number: G-CAB7706.100
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
From 352.00€
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Item number: ATA-HPA015577.100
Protein function: Receptor for extracellular adenine nucleotides such as ADP (PubMed:9442040, PubMed:9038354, PubMed:25822790). In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation...
Keywords: | Anti-P2Y1, Anti-P2RY1, Anti-ADP receptor, Anti-P2Y purinoceptor 1, Anti-Purinergic receptor |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 300.00€
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