31 products were found matching "K04260"!

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. PTGER3 antibody detects Prostaglandin E2 receptor EP3 subtype, a G protein-coupled receptor (GPCR) encoded by the PTGER3 gene located on chromosome 1p31.1. PTGER3 mediates the biological effects of prostaglandin E2 (PGE2), a key lipid...

Prostaglandin E2 (Cay-14010) exerts its effects through four separate G-protein coupled receptors (EP1, EP2, EP3, and EP4). L-798,106 is a highly selective EP3 receptor antagonist with Ki values of 0.3, 916, >5,000, and >5,000 nM at EP3, EP4, EP1, and EP2, respectively. At 0.2 µM, it blocks the EP3 agonist activity...

The biological effects of prostaglandin E2 (PGE2) are mediated through interaction with four distinct membrane-bound G-protein coupled EP receptors: EP1, EP2, EP3, and EP4. As a result of splice variation, the EP3 receptor can be expressed as multiple isoforms that differ in the length and sequence of their...

L-826,266 is a potent and selective competitive antagonist of the prostaglandin E2 receptor subtype EP3 (Ki = 0.8 nM). It also binds to the EP4 receptor (Ki = 715 nM) but does not bind to EP1 or EP2 receptors up to a concentration of 5,000 nM. L-826,266 inhibits vasoconstriction induced by the EP3 agonist...

Description: L-798106 (CM9) is a selective and potent prostaglandin-like EP3 receptor antagonist that inhibits EP4, EP1, and EP2 receptors, suppresses levels of pro-inflammatory cytokines in atherosclerosis, and attenuates PGE2-induced cough. Target: Prostaglandin Receptor. Smiles:...

Protein function: Receptor for prostaglandin E2 (PGE2), the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Prostaglandin E receptor 3, EP3 Protein function: Receptor for prostaglandin E2 (PGE2), the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter...

Protein function: Receptor for prostaglandin E2 (PGE2) (PubMed:8307176, PubMed:7883006, PubMed:8117308, PubMed:8135729, PubMed:7981210). The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G(i) proteins, and to an elevation of intracellular calcium (PubMed:7883006,...

In 1X PBS, pH 7.4, with 0.09% sodium azide. PTGER3 is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine...

DG-041 is an antagonist of the prostaglandin E2 (PGE2, Cay-14010) receptor subtype EP3 (IC50 = 8.1 nM in a calcium mobilization assay). It is selective for EP3 over DP1, EP1, and TP receptors (IC50s = 131, 486, and 742 nM, respectively, in calcium mobilization assays) as well as EP2, EP4, IP, FP, and DP2/CRTH2...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-53aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: MKETRGYGGD APFCTRLNHS YTGMWAPERS AEARGNLTRP PGSGEDCGSV SVA. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity:...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...