48 products were found matching "K04229"!

Oxytocin is an abundant neuropeptide that exerts a wide spectrum of central and peripheral effects. In the context of human reproduction, oxytocin promotes uterine contractions and lactation. It is the most commonly used drug for labor induction. Oxytocin receptors are expressed in the uterus and in mammary glands,...

A nonpeptide oxytocin receptor antagonist (Ki = 19 and 4.6 nM for the rat uterine and human uterine receptors, respectively), selective for oxytocin receptors over human AVP receptors V1A and -V2 (Kis = 3,200 and >10,000 nM for the human platelet and kidney receptors, respectively) and rat AVP receptor V2 (Ki =...

Atosiban is a peptide analog of oxytocin (Cay-11799) that antagonizes the human oxytocin receptor (Ki = 81 nM). It also binds the vasopressin V1a receptor (Ki = 3.5 nM). Because of its effects on the oxytocin receptor, atosiban has tocolytic actions in the acute phase of imminent preterm birth.Formal Name: cyclic...

The protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during...

PF-3274167 is an oxytocin receptor antagonist (Ki = 9.5 nM). It is selective for the oxytocin receptor over the vasopressin receptors V1A and V2 (Kis = 1,120 and 10,000 nM, respectively).Formal Name: 5-[3-[3-(2-chloro-4-fluorophenoxy)-1-azetidinyl]-5-(methoxymethyl)-4H-1,2,4-triazol-4-yl]-2-methoxy-pyridine. CAS...

L-368,899 is a non-peptide oxytocin receptor antagonist (IC50s = 8.9 and 26 nM in radioligand binding assays using isolated human and rat uterus, respectively). It is selective for oxytocin receptors over vasopressin V1a and V2 receptors (IC50s = 370 and 570 nM, respectively). L-368,899 reduces oxytocin-induced...

Carbetocin is an oxytocin receptor agonist and a peptide analog of oxytocin (Cay-11799). It selectively binds to oxytocin receptors over vasopressin V2 receptors (Kds = 1.96 and 61.3 nM, respectively). Carbetocin induces contraction of isolated rat uterine strips (EC50 = 48 nM) and inhibits oxytocin-induced...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat OXTR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat OXTR. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human OXTR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human OXTR. Next,...

This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Oxytocin Receptor (OXTR). INDIGO's ADRB1 reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the OXTR. In addition to OXTR Reporter Cells, this kit provides two...

This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Oxytocin Receptor (OXTR). INDIGO's ADRB1 reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the OXTR. In addition to OXTR Reporter Cells, this kit provides two...