36 products were found matching "K04223"!
No results were found for the filter!
GR87389
Item number: Cay44018-1
An NK2 receptor antagonist, inhibits NKA binding in rat hippocampal, urinary bladder, and duodenal membranes (Kis = 4, 5.2, and 14 nM, respectively), inhibits GR64349-induced contraction of isolated human detrusor muscle at 30, 100, and 300 nM. SMILES:...
| Keywords: | Boc-Ala-Ala-D-Trp-Phe-D-Pro-Pro-Nle-NH2,... |
| Application: | NK2 receptor antagonist |
| CAS | 141663-86-7 |
| MW: | 900.09 D |
From 78.00€
*
GR83074 (trifluoroacetate salt)
Item number: Cay44017-1
GR83074 is a peptide antagonist of the neurokinin-2 (NK2) receptor. It selectively inhibits neurokinin A-induced contractions in rat colon muscularis mucosae, which express NK2 receptors, over substance P-induced contractions in guinea pig ileum longitudinal smooth muscle strips, which express NK1 receptors (pKbs =...
| Keywords: | Boc-Arg-Ala-D-Trp-Phe-D-Pro-Pro-Nle-NH2,... |
| Application: | NK2 receptor peptide antagonist |
| MW: | 985,2 D |
From 153.00€
*
GR64349 (acetate)
Item number: Cay42915-1
A peptide agonist of the NK2 receptor, selectively induces contractions in isolated rat colon muscularis mucosae, which endogenously express NK2 receptors, over isolated guinea pig ileum longitudinal smooth muscle and everted rat portal vein, which endogenously express NK1 and NK3 receptors, respectively (EC50s =...
| Keywords: | [Lys3,Gly8-R-Lac-Leu9]Neurokinin A (3-10), [Lys3,Gly8-R-Lac-Leu9]NKA (3-10), [Lys3,Gly8-R-gamma-lactam-Leu9]NKA (3-10),... |
| Application: | Peptide NK2 receptor (TAC2R, tachykinin receptor 2) agonist |
| MW: | 981.18 D |
From 483.00€
*
R 396 (trifluoroacetate salt)
Item number: Cay43083-10
A peptide antagonist of the NK2B receptor (pA2 = 7.63), selective for the NK2B receptor over NK1, NK2A, and NK3 receptors (pA2s = <5, 5.41, and <5, respectively), intracerebroventricular administration inhibits NKA- but not substance P-induced increases in mean arterial blood pressure, heart rate, face washing, and...
| Keywords: | Ac-Leu-Asp-Gln-Trp-Phe-Gly-NH2, N-acetyl-L-leucyl-L-alpha-aspartyl-L-glutaminyl-L-tryptophyl-L-phenylalanyl-glycinamide,... |
| Application: | NK2B receptor peptide antagonist |
| MW: | 805.89 D |
From 70.00€
*
Human Neurokinin A / NK2R ELISA Kit
Item number: G-HUFI02889.96
| Application: | ELISA |
| Species reactivity: | human |
698.00€
*
Mouse Neurokinin A / NK2R ELISA Kit
Item number: G-MOFI01133.96
| Application: | ELISA |
| Species reactivity: | mouse |
698.00€
*
Men 10376
Item number: LKT-M1752.1
An NK2 (tachykinin receptor 2) antagonist.
| Application: | NK2 antagonist |
| MW: | 1081,25 D |
From 114.00€
*
MEN10376
Item number: Cay31142-1
MEN10376 is a peptide neurokinin-2 (NK2) receptor antagonist. It inhibits contractions induced by neurokinin A (NKA) in endothelium-deprived isolated rabbit pulmonary artery (pA2 = 8.08), which is endogenously enriched in NK2 receptors. It is selective for NK2 receptors in isolated rabbit pulmonary artery over NK2...
| Keywords: | Asp-Tyr-Trp-Val-Trp-Trp-Lys-NH2, DYWVWWK-NH2,... |
| Application: | Neurokinin-2 (NK2) receptor antagonist |
| CAS | 135306-85-3 |
| MW: | 1081.2 D |
From 105.00€
*
GR159897
Item number: Cay32774-1
GR159897 is a nonpeptide antagonist of the neurokinin-2 (NK2) receptor. It binds to NK2 receptors (Ki = 0.32 nM) and is selective for NK2 over NK1 and NK3 receptors in radioligand binding assays (Kis = 5,010 and >1,000 nM, respectively). GR159897 inhibits contractions induced by the NK2 receptor agonist GR64349 in...
| Keywords: | 5-fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulfinyl]methyl]-1-piperidinyl]ethyl]-1H-indole |
| Application: | Nonpeptide NK2 receptor antagonist |
| CAS | 158848-32-9 |
| MW: | 414.5 D |
From 69.00€
*
WIN 66,306
Item number: Cay33161-5
WIN 66,306 is a cyclic heptapeptide antagonist of neurokinin-1 (NK1) and NK2 receptors originally isolated from A. flavipes. It binds to NK1 and NK2 receptors (Kis = 8 and 3.8 µM, respectively, for the human receptors) and inhibits contractions induced by substance P (Cay-24035) in isolated guinea pig ileum in a...
| Keywords: | cyclo[glycyl-L-tryptophyl-L-prolylglycyl-L-valylglycyl-(betaR)-beta-hydroxy-3-(3-methyl-2-butenyl)-L-tyrosyl] |
| Application: | TACR1 / TACR2 peptide antagonist |
| CAS | 151928-32-4 |
| MW: | 800.9 D |
From 371.00€
*
Anti-TACR2
Item number: ATA-HPA076573.100
Protein function: This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P. [The UniProt...
| Keywords: | Anti-SKR, Anti-NK2R, Anti-TACR2, Anti-NK-2R, Anti-NK-2 receptor, Anti-Substance-K receptor, Anti-Tachykinin receptor 2,... |
| Application: | ICC |
| Host: | Rabbit |
| Species reactivity: | human |
From 369.00€
*
GR94800
Item number: Cay38773-1
GR94800 is a synthetic peptide neurokinin-2 (NK2) receptor antagonist (Ki = 1 nM). It is selective for NK2 over NK3 (Ki = 1,000 nM). GR94800 (0.1 and 1 µM) decreases balloon distension-induced submaximal and maximal atropine-resistant ascending excitatory reflex (AER) in isolated guinea pig ileum circular...
| Keywords: | Benzoyl-Ala-Ala-trp-Phe-pro-Pro-Nle-NH2, GR98400,... |
| Application: | NK2 receptor (tachykinin receptor 2, TACR2) antagonist, synthetic peptide |
| CAS | 141636-65-9 |
| MW: | 904.1 D |
From 45.00€
*