85 products were found matching "K04179"!

ELISA Type: Sandwich. Detection Range: 78.125-5000µg/mL. Sensitivity: 46.875pg/ ml. Sample Types: Serum, Plasma. Protein function: High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. CCR4,C-C chemokine receptor type 4 is a protein that in humans is encoded by the CCR4 gene. CCR4 has also recently been designated CD194(cluster of differentiation 194). The protein encoded by this gene belongs to the G protein-coupled receptor family. It is a...

Chemokine (C-C motif) receptor 4 (CCR4) antagonist is an antagonist of CCR4. It inhibits activation of CCR4 by chemokine (C-C motif) ligand 22 (CCL22) in a [35S]GTPgammaS assay and also inhibits chemotaxis in human and mouse CCR4-expressing B300-19 cells (IC50s = 18, 140, and 39 nM, respectively). CCR4 antagonist...

In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various...

Protein function: High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating...

Protein function: High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol- calcium second messenger system. Could play a role in lipopolysaccharide (LPS)-induced endotoxic shock. In the CNS, could...

AZD 2098 is a CC chemokine receptor 4 (CCR4) antagonist. AZD 2098 inhibits CCL22-induced calcium flux in CHO cells expressing human recombinant CCR4 (IC50 = 31.6 nM) and CCL22- and CCL17-mediated Th2 cell chemotaxis (IC50 = 501.2 nM for both). AZD 2098 is selective for CCR4 over CXCR1, CXCR2, CCR1, CCR2b, CCR5,...

Protein function: High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating...

Protein function: High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CCR4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CCR4. Next,...

Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 1-360aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MNPTDIADTT LDESIYSNYY LYESIPKPCT KEGIKAFGEL FLPPLYSLVF VFGLLGNSVV VLVLFKYKRL RSMTDVYLLN LAISDLLFVF SLPFWGYYAA DQWVFGLGLC...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 309-360aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: EKFRKYILQL FKTCRGLFVL CQYCGLLQIY SADTPSSSYT QSTMDHDLHD AL. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological...