46 products were found matching "K04173"!

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human FPR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human FPR2. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse FPR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse FPR2. Next,...

WRW4 is a peptide antagonist of formyl peptide receptor 2 (FPR2, IC50 = 0.23 µM) and FPR3, previously known as FPR-like 1 (FPRL1) and FPRL2, respectively. It inhibits increases in intracellular calcium and chemotaxis induced by the FPR1 and FPR2 agonist WKYMVm (Cay-33589) in RBL-2H3 cells expressing FPR2 and by the...

N-Formyl-Met-Leu-Phe (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPRs, Ki = 0.8 pM), which are mainly localized on polymorphonuclear and mononuclear phagocytes. Activation of FPRs by fMLF leads to cellular activation, which is characterized by cellular polarization, chemotaxis,...

Formyl peptide receptor 2 (FPR2) is a G protein-coupled receptor (GPCR). It is encoded by FPR2 and is expressed in lung, kidney, spleen, placenta, macrophages, peripheral blood leukocytes, synovial fibroblasts, T cells, and intestinal epithelial cells. FPR2 is coupled to the Gi/o transduction pathway and is...

ELISA Type: CLIA. Sensitivity: 9.375 pg/mL. Range: 15.625--1000 pg/mL. Protein function: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors (PubMed:1374236). Binding of FMLP to the receptor causes activation of neutrophils (PubMed:1374236). This response is...

ELISA Type: CLIA. Sensitivity: 7.5 pg/mL. Range: 12.5--800 pg/mL. Protein function: High affinity receptor for N-formyl-methionyl peptides (FMLP), which are powerful neutrophil chemotactic factors (PubMed:12218158, PubMed:10477558, PubMed:19387439). Stimulates chemotaxis in immune cells to site of infection or...

ELISA Type: Sandwich. Sensitivity: 18.75pg/mL. Range: 31.25--2000pg/mL. Protein function: High affinity receptor for N-formyl-methionyl peptides (FMLP), which are powerful neutrophil chemotactic factors (PubMed:12218158, PubMed:10477558, PubMed:19387439). Stimulates chemotaxis in immune cells to site of infection or...

TC-FPR 43 is an agonist of formyl peptide receptor 1 (FPR1) and FPR2, which was previously known as formyl peptide receptor-like 1 (FPRL1). TC-FPR 43 induces calcium flux in CHO cells expressing human FPR2, Galpha15, and aequorin (EC50 = 0.044 µM) and in CHO-K1 cells expressing either human FPR1, human FPR2, mouse...

MMK1 is an agonist of formyl peptide receptor 2 (FPR2), which was previously known as formyl peptide receptor-like 1 (FPRL1). MMK1 induces calcium flux in CHO cells expressing human FPR2 and Galpha16 (EC50 = alpha16 alone or in combination with FPR1 (EC50s = >10,000 nM for both). It induces chemotaxis of isolated...