53 products were found matching "K04173"!

N-Formyl-Met-Leu-Phe (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPRs, Ki = 0.8 pM), which are mainly localized on polymorphonuclear and mononuclear phagocytes. Activation of FPRs by fMLF leads to cellular activation, which is characterized by cellular polarization, chemotaxis,...

Formyl peptide receptor 2 (FPR2) is a G protein-coupled receptor (GPCR). It is encoded by FPR2 and is expressed in lung, kidney, spleen, placenta, macrophages, peripheral blood leukocytes, synovial fibroblasts, T cells, and intestinal epithelial cells. FPR2 is coupled to the Gi/o transduction pathway and is...

TC-FPR 43 is an agonist of formyl peptide receptor 1 (FPR1) and FPR2, which was previously known as formyl peptide receptor-like 1 (FPRL1). TC-FPR 43 induces calcium flux in CHO cells expressing human FPR2, Galpha15, and aequorin (EC50 = 0.044 µM) and in CHO-K1 cells expressing either human FPR1, human FPR2, mouse...

MMK1 is an agonist of formyl peptide receptor 2 (FPR2), which was previously known as formyl peptide receptor-like 1 (FPRL1). MMK1 induces calcium flux in CHO cells expressing human FPR2 and Galpha16 (EC50 = alpha16 alone or in combination with FPR1 (EC50s = >10,000 nM for both). It induces chemotaxis of isolated...

WKYMVm is a synthetic peptide agonist of formyl peptide receptor 1 (FPR1) and FPR2, which was previously known as formyl peptide receptor-like 1 (FPRL1). It induces calcium mobilization in ETFR rat basophilic leukemia cells transfected with FPR1 or FPR2 when used at a concentration of 0.1 nM. WKYMVm stimulates...

Protein function: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors (PubMed:1374236). Binding of FMLP to the receptor causes activation of neutrophils (PubMed:1374236). This response is mediated via a G-protein that activates a phosphatidylinositol-calcium...

PBP 10 is a peptide formyl peptide receptor 2 (FPR2) antagonist (IC50 = 60 nM). It is active against E. coli, P. aeruginosa, and S. pneumoniae when used at concentrations ranging from 0.1 to 100 µM.Formal Name:...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human FPR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human FPR2. Next,...

Organism: Mus musculus (Mouse). Source: in vitro E.coli expression system. Expression Region: 1-351aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MESNYSIHLN GSEVVVYDST ISRVLWILSM VVVSITFFLG VLGNGLVIWV AGFRMPHTVT TIWYLNLALA DFSFTATLPF LLVEMAMKEK WPFGWFLCKL VHIVVDVNLF...

Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-29aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-GST-tagged and C-terminal Myc-tagged. Target Protein Sequence: MESNYSIHLN GSEVVVYDST ISRVLWILS. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity:...