17 products were found matching "K04168"!

Recombinant CHO-K1 cells stably overexpress human bombesin receptor subtype 1 (BB1), or neuromedin B receptor (NMBR), on the surface and contain high levels of G protein Galphaq to couple with the receptor in downstream signaling pathways.

PD 168368 is a competitive antagonist of neuromedin B (NMB) receptors (Kis = 15-45 nM for rat and human receptors expressed in various cell lines). It blocks the elevation of intracellular calcium and release of inositol phosphate induced by NMB in cells expressing NMB receptors. PD 168368 is selective for NMB...

Receptor for neuromedin-B. Belongs to the G-protein coupled receptor 1 family. Protein function: Receptor for neuromedin-B (PubMed:1655761). Contributes to the maintenance of basal sigh rate through signaling in the pre- Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...

Host Species: Rabbit. Isotype: IgG. Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity purification. Target Name: NMBR. Antigen Species: Human

Description: PD 168368 is a novel, potent, competitive and selective nonpeptide neuromodulin B receptor (NMB-R) antagonist with inhibitory effects on the gastrin-releasing peptide receptor (GRPR).PD 168368 is a potent mixed agonist of FPR1/FPR2/FPR3. Target: Bombesin Receptor. Smiles:...

A nonpeptide antagonist of BB1 and BB2 (Kis = 0.17 and 1 nM, respectively), induces calcium mobilization in HL-60 cells expressing FPR1 or FPR2/ALX (EC50s = 0.31 and 0.66 µM, respectively), inhibits the proliferation of C6 glioma cells (IC50 = 2 µM), increases social interaction in the social interaction test in...

Protein function: Receptor for neuromedin-B. [The UniProt Consortium]

Protein function: Receptor for neuromedin-B. [The UniProt Consortium]

Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: May be stored at 4°C for...

Neuromedin B Receptor (NMBR) is an 80kD, 390aa G-protein coupled 7-transmembrane glycoprotein receptor for bombesin-like peptides, binding Neuromedin B with high affinity and GRP (gastrin releasing peptide) with lower affinity. Neuromedin B R expression in the olfactory and central thalamic regions of the brain...

Custom conjugation services for this antibody as available (eg. labeling of Anti-NMBR with HRP. Available labels are AF: AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750. Proteins: HRP, Alkaline Phosphatase, Streptavidin. Tandems: APC, APC/Cy7, APC/AF750, APC/iFluor(TM) 700, APC/iFluor(TM) 750, PE, PE/Cy5,...