- Search results for K04163
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33 products were found matching "K04163"!
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Item number: CSB-CF010899HU.100
Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 1-479aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MMDVNSSGRP DLYGHLRSFL LPEVGRGLPD LSPDGGADPV AGSWAPHLLS EVTASPAPTW DAPPDNASGC GEQINYGRVE KVVIGSILTL ITLLTIAGNC LVVISVCFVK...
Keywords: | HTR7, 5-HT7, 5-HT-X, 5-HT-7, Serotonin receptor 7, 5-hydroxytryptamine receptor 7, Recombinant Human 5-hydroxytryptamine... |
Application: | Activity not tested |
Expressed in: | E.coli in vitro |
Origin: | human |
MW: | 56.4 kD |
From 1,413.00€
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Item number: Cay17081-10
The transduction of neurobehavioral effects by serotonin (5-hydroxy tryptamine, 5-HT) is mediated by at least seven major 5-HT receptor subtypes. SB-269970 is a potent 5-HT7A antagonist (pKi = 8.9) that demonstrates >50-fold binding selectivity over 5-HT5A and >250-fold selectivity over 5-HT1, 5-HT2, 5-HT4, 5-HT6,...
Keywords: | 3-[[(2R)-2-[2-(4-methyl-1-piperidinyl)ethyl]-1-pyrrolidinyl]sulfonyl]-phenol, monohydrochloride |
Application: | 5-HT7A antagonist |
CAS | 261901-57-9 |
MW: | 389 D |
From 130.00€
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Item number: Cay29659-10
LP-211 is an agonist of the serotonin (5-HT) receptor subtype 5-HT7 (Ki = 0.58 nM). It is selective for 5-HT7 over 5-HT1A and dopamine D2 receptors (Kis = 188 and 142 nM, respectively). It induces relaxation of isolated guinea pig ileum precontracted by substance P (Cay-24035, EC50 = 0.6 µM). LP-211 (100 nM)...
Keywords: | 4-[1,1'-biphenyl]-2-yl-N-[(4-cyanophenyl)methyl]-1-piperazinehexanamide |
Application: | 5-HT7 agonist |
CAS | 1052147-86-0 |
MW: | 466.6 D |
From 43.00€
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-30 %
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Item number: ARG64923.100
Protein function: This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. [The UniProt Consortium]
Keywords: | Anti-HTR7, Anti-5-HT7, Anti-5-HT-X, Anti-5-HT-7, Anti-Serotonin receptor 7, Anti-5-hydroxytryptamine receptor 7 |
Application: | ELISA, WB |
Host: | Goat |
Species reactivity: | human |
784.00€
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548.80€
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Item number: 200-401-I13
Anti-Serotonin Receptor 7 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-Serotonin Receptor 7 from human, mouse, dog and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Serotonin Receptor 7 from other sources has...
Keywords: | Anti-Htr7, Anti-GPRFO, Anti-5-HT7, Anti-5-HT-X, Anti-5-HT-7, Anti-Serotonin receptor 7, Anti-5-hydroxytryptamine receptor 7 |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
756.00€
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Item number: LKT-V5870.100
Vortioxetine exhibits neuromodulatory, antidepressant, anxiolytic, and cognition enhancing activities. Vortioxetine modulates serotonin levels in the brain by inhibiting the serotonin transporter (SERT) and 5-HT3A/7 receptors, acting as a partial agonist at the 5-HT1B receptor, and acting as a full agonist at the...
Application: | 5-HT3-receptor antagonist, 5-HT7-receptor antagonist, 5-HT1A-receptor agonist |
CAS | 508233-74-7 |
MW: | 298.45 D |
From 90.00€
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Item number: NSJ-R35373-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Hydroxytryptamine receptor 7, 5-HT7 receptor Protein function: This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a...
Keywords: | Anti-HTR7, Anti-5-HT7, Anti-5-HT-7, Anti-5-HT-X, Anti-Serotonin receptor 7, Anti-5-hydroxytryptamine receptor 7, HTR7... |
Application: | WB, ELISA (peptide) |
Host: | Goat |
Species reactivity: | human |
755.00€
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Item number: Cay23694-1
Vortioxetine is a multimodal serotonergic agent that acts as a serotonin (5-HT, Cay-14332) reuptake inhibitor (Ki = 1.6 nM) and binds to the 5-HT1A, 5-HT1B, 5-HT3A, and 5-HT7 receptors (Kis = 15, 33, 3.7, and 19 nM, respectively). It also binds to the beta1-adrenergic receptor (Ki = 46 nM). It acts as an antagonist...
Keywords: | 1-[2-[(2,4-dimethylphenyl)thio]phenyl]-piperazine, monohydrobromide |
Application: | Serotonergic agent |
CAS | 960203-27-4 |
MW: | 379.4 D |
From 44.00€
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Item number: Cay17287-1
LP44 is a full agonist of the serotonin 5-HT7 receptor (Ki = 0.22 nM) that displays 200- and greater than 1,000-fold selectivity over 5-HT1A (Ki = 52.7 nM) and 5-HT2A (Ki = 326 nM) receptors, respectively. It can induce relaxation of substance P-induced guinea pig ileum contraction with an EC50 value of 2.56...
Keywords: | 4-[2-(methylthio)phenyl]-N-(1,2,3,4-tetrahydro-1-naphthalenyl)-1-piperazinehexanamide, monohydrochloride |
Application: | Serotonin 5-HT7 receptor agonist |
CAS | 824958-12-5 |
MW: | 488.1 D |
From 60.00€
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Item number: Cay9000570-25
Lurasidone is an atypical antipsychotic that binds to dopamine D2, serotonin (5-HT) receptor subtypes 5-HT2A, 5-HT1A, and 5-HT7, and alpha2C-adrenergic receptors (Kis = 1.68, 2.03, 6.75, 0.495, and 10.8 nM, respectively). In vivo, pre-training administration of lurasidone (1 and 3 mg/kg) reverses impairment in...
Keywords: | (3aR,4S,7R,7aS)-2-[[(1R,2R)-2-[[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-4,7-methano-1... |
Application: | HTR1A / HTR2 / HTR7 / DRD2 modulator |
CAS | 367514-87-2 |
MW: | 492.7 D |
From 77.00€
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Item number: Cay20642-1
AS-19 is an agonist of the serotonin (5-HT) receptor subtype 5-HT7 (Ki = 0.6 nM). It is selective for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Kis = 89.7, 490, 6.6 and 98.5 nM, respectively), as well as sigma-1 and imidazoline I2 receptors (Kis = 657 and 282 nM, respectively). AS-19 increases...
Keywords: | 1,2S,3,4-tetrahydro-N,N-dimethyl-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-2-naphthalenamine |
Application: | 5-HT7 agonist |
CAS | 1000578-26-6 |
MW: | 283.4 D |
From 77.00€
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Item number: ATA-HPA073617.100
Protein function: This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. [The UniProt Consortium] Buffer: 40%...
Keywords: | Anti-HTR7, Anti-5-HT7, Anti-5-HT-X, Anti-5-HT-7, Anti-Serotonin receptor 7, Anti-5-hydroxytryptamine receptor 7 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | human |
From 335.00€
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