112 products were found matching "K03671"!

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Thioredoxin, mitochondrial also known as thioredoxin-2 is a protein that in humans is encoded by the TXN2 gene on chromosome 22. It is mapped to 22q12.3. This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional...

Ferroptocide is an inhibitor of thioredoxin (Trx) and a derivative of pleuromutilin (Cay-19452). It inhibits Trx activity in ES-2 ovarian cancer cells when used at a concentration of 20 µM and is cytotoxic to ES-2 cells (IC50 = 1.6 µM). Ferroptocide (5 µM) induces ferroptosis in ES-2 cells, an effect that can be...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human Trx. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human Trx. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat Trx. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat Trx. Next, Avidin...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse Trx. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse Trx. Next,...

Cayman's Thioredoxin Fluorescent Activity Assay Kit provides a convenient method of detecting Trx activity in cell lysate. Measurement of the Trx activity is based on the reduction of eosin-labeled insulin disulfides by Trx. The reduction of insulin disulfides results in a release of eosin and an increase in...

White to off-white powder. Soluble in DMSO, ethanol or DMF (all 15mg/ml). Slightly soluble in water (~1mg/ml). Chemical. CAS: 141400-58-0. Formula: C7H12N2S2. MW: 188.3. PX-12 is a competitive, irreversible inhibitor of thioredoxin 1 (Trx1), acting by binding to Cys73 of this enzyme. High levels of Trx-1 have been...

Protein function: Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity. [The UniProt Consortium]

Protein function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to...

Protein function: Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity. [The UniProt Consortium]

Protein function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to...

Truncated thioredoxin 1 (Trx80) is a C-terminally truncated cleavage product of the oxidoreductase Trx1 that acts as a cytokine. It is expressed primarily in monocytes but also in T cells, activated platelets, and cytotrophoblasts, and localizes to the cell surface. Trx80 contains three cysteines but does not have...