- Search results for K03259
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101 products were found matching "K03259"!
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Item number: Cay35894-10
4E2RCat is an inhibitor of the protein-protein interaction between eukaryotic translation initiation factor 4E (eIF4E) and eIF4G (IC50 = 13.5 µM). It reduces mRNA translation without inducing apoptosis in L-132 cells when used at a concentration 12.5 µM. 4E2RCat (6 µM) decreases intracellular and extracellular...
Keywords: | 2-chloro-5-[5-[[4-oxo-3-(phenylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]-2-furanyl]-benzoic acid |
Application: | eIF4E-eIF4G protein-protein interaction inhibitor |
CAS | 432499-63-3 |
MW: | 455.9 D |
From 34.00€
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Item number: ELK-ELK8552.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat eIF4E. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat eIF4E. Next,...
Keywords: | eIF4E, Eif4e, eIF-4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein, Eukaryotic translation initiation factor 4E |
Application: | ELISA |
Species reactivity: | rat |
From 365.00€
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Item number: NSJ-R20466-0.1ML
Antibody in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide. This antibody reacts to human eIF4E only when phosphorylated at Ser209. There is no cross-reactivity to eIF4E that is not phosphorylated. Protein function: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the...
Keywords: | Anti-phospho-eIF4E, Anti-phospho-eIF-4E, Anti-phospho-EIF4EL1, Anti-phospho-eIF-4F 25 kDa subunit, Anti-phospho-mRNA... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
737.00€
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Item number: Cay15362-1
In eukaryotes, a set of initiation factors (eIFs) interact with ribosomal subunits to initiate mRNA translation. A major step in initiation is the assembly of a large multiprotein complex that includes the cap-binding protein eIF4E and the multidomain adaptor protein eIF4G. 4EGI-1 is an inhibitor of the initiation...
Keywords: | eIF4E/eIF4G Interaction Inhibitor, alpha-[2-[4-(3,4-dichlorophenyl)-2-thiazolyl]hydrazinylidene]-2-nitro-benzenepropanoic... |
Application: | Translation initiation inhibitor |
CAS | 315706-13-9 |
MW: | 451.3 D |
From 60.00€
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Item number: A301-154A
Protein function: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and...
Keywords: | Anti-eIF4E, Anti-EIF4E, Anti-eIF-4E, Anti-EIF4EL1, Anti-eIF-4F 25 kDa subunit, Anti-mRNA cap-binding protein,... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: ARG51723.100
Protein function: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and...
Keywords: | Anti-phospho-EIF4E, Anti-phospho-eIF4E, Anti-phospho-eIF-4E, Anti-phospho-EIF4EL1, Anti-phospho-eIF-4F 25 kDa subunit,... |
Application: | ICC, IF, IHC (paraffin), WB |
Host: | Rabbit |
Species reactivity: | human |
From 436.00€
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Item number: Cay22989-1
Briciclib is a water soluble derivative of ON 013100, a small molecule that binds to and inhibits eukaryotic translation initiation factor 4E (eIF4E). Briciclib inhibits proliferation of JEKO-1 and Mino mantle cell leukemia (MCL), MCF-7 and MDA-MB-231 breast, AGS gastric, and OE19, OE33, and LFO-1 esophageal cancer...
Keywords: | ON-014185, 2-methoxy-5-[[[(1E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]-phenol 1-(dihydrogen phosphate) |
Application: | eIF4E binding, cap-dependent translation inhibitor |
CAS | 865783-99-9 |
MW: | 474.4 D |
From 50.00€
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Item number: Cay25150-100
Eukaryotic translation initiation factor 4E (eIF4E) is a component of the eIF4 complex that specifically binds to the methyl-7-guanosine cap structure at the 5' end of eukaryotic mRNA to initiate translation. Nuclear eIF4E promotes export of mRNAs that contain the eIF4E sensitivity element (4E-SE) to the cytosol...
Keywords: | eIF4E, eIF4E, eIF-4E, eIF-4E, EIF4EL1, eIF-4F 25 kDa subunit, eIF-4F 25 kDa subunit, mRNA cap-binding protein... |
Expressed in: | E.coli |
Origin: | human |
642.00€
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Item number: ARG51206.100
Protein function: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and...
Keywords: | Anti-EIF4E, Anti-eIF4E, Anti-eIF-4E, Anti-EIF4EL1, Anti-eIF-4F 25 kDa subunit, Anti-mRNA cap-binding protein,... |
Application: | ICC, IF, IHC (paraffin), WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 436.00€
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Item number: ARG56163.100
Protein function: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. [The UniProt Consortium]
Keywords: | Anti-EIF4E2, Anti-EIF4EL3, Anti-eIF4E type 2, Anti-eIF-4E type 2, Anti-eIF4E-like protein 4E-LP, Anti-mRNA cap-binding... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
624.00€
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Item number: ARG65706.100
Protein function: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and...
Keywords: | Anti-eIF4E, Anti-EIF4E, Anti-eIF-4E, Anti-EIF4EL1, Anti-eIF-4F 25 kDa subunit, Anti-mRNA cap-binding protein,... |
Application: | WB, IHC (paraffin) |
Host: | Rabbit |
Species reactivity: | human |
624.00€
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Item number: A301-153A
Protein function: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and...
Keywords: | Anti-eIF4E, Anti-EIF4E, Anti-eIF-4E, Anti-EIF4EL1, Anti-eIF-4F 25 kDa subunit, Anti-mRNA cap-binding protein,... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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