18 products were found matching "K03240"!

Protein function: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. [The UniProt Consortium]

Protein function: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. [The UniProt Consortium]

Protein function: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. [The UniProt Consortium]

Protein function: Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 90% and to rat: 88%

Protein function: Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 84% and to rat: 89%

Protein function: Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. [The UniProt Consortium]

2BAct is an activator of eukaryotic translation initiation factor 2B (eIF2B, EC50 = 33 nM in a reporter assay). It enhances eIF2B activity in primary fibroblasts isolated from Eif2b5R191H mutant (R191H) mouse embryos (EC50 = 7.3 nM), a model of vanishing white matter (VWM) leukodystrophy. In vivo, 2BAct (30 mg/kg)...

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy...

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy...

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy...

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy...