25 products were found matching "K02622"!

Nalidixic acid is a quinolone antibiotic. It is active against E. coli, Pasturella, K. pneumoniae, A. aerogenes, Proteus, Salmonella, and Shigella with minimum bacteriostatic concentrations (MBCs) ranging from 0.5 to 25 µg/ml. Nalidixic acid increases survival in mouse models of systemic K. pneumoniae, A. aerogenes,...

Enoxacin is a fluoroquinolone antibiotic. It is active against clinical isolates of a variety of Gram-positive and Gram-negative bacteria, including S. aureus, E. coli, K. pneumoniae, P. aeruginosa, and S. marcescens (MIC50s = 1, 0.12, 0.25, 0.5, and 1 mg/L, respectively). Enoxacin inhibits S. aureus DNA gyrase...

Levofloxacin is a fluoroquinolone antibiotic and the active stereoisomer of ofloxacin (Cay-22891). It is active against S. aureus, S. epidermidis, B. subtilis, E. coli, P. aeruginosa, and K. pneumoniae (MICs = 0.25, 0.25, 0.5, 0.03, 4, and 0.25 µg/ml, respectively). Levofloxacin inhibits S. aureus DNA gyrase and...

Ofloxacin is a broad-spectrum fluoroquinolone antibiotic that prevents supercoiling of bacterial chromosomes by DNA gyrase. It is active against Gram-positive and Gram-negative bacteria with MIC90s ranging from 0.39 to 3.13 µg/ml for clinical isolates of S. aureus, S. epidermidis, S. pyogenes, and S. faecalis and...

Nadifloxacin is a fluoroquinolone antibiotic. It is active against clinical isolates of S. aureus, coagulase-negative staphylococci, P. acnes, and P. granulosum (MIC50s = 0.03, 0.06, 0.25, and 0.125 mg/L, respectively). Nadifloxacin inhibits the activities of DNA gyrase and topoisomerase IV (IC50s = 8.83 and 3.22...

Gemifloxacin is a fluoroquinolone antibiotic that is effective against C. pneumoniae and M. tuberculosis (MIC50s = 0.25 and 8 µg/ml, respectively). Quinolones, including gemifloxacin, inhibit bacterial DNA gyrase and other topoisomerases. Formulations containing gemifloxacin are useful against respiratory tract...

Moxifloxacin is a fluoroquinolone antibiotic. It is active against 390 clinical isolates of aerobic and anaerobic Gram-positive and Gram-negative bacteria (MIC90s = =0.25 µg/ml), as well as clinical isolates of methicillin-susceptible and -resistant S. aureus (MIC90s = 0.12 and 2 µg/ml, respectively). Moxifloxacin...

Clinafloxacin is a fluoroquinolone antibiotic that displays broad-spectrum antibacterial activity against Gram-positive, Gram-negative, and anaerobic pathogens by inhibiting the bacterial regulatory enzyme DNA gyrase (IC50 = 0.92 µg/ml) as well as topoisomerase IV (IC50 = 1.62 µg/ml).Formal Name:...

Sitafloxacin is a fluoroquinolone antibiotic. It is active against a panel of clinical isolates from a variety of bacterial species (MIC50s = =0.006-1.56 µg/ml), including methicillin-resistant strains of S. aureus and S. epidermidis and ofloxacin-resistant P. aeruginosa (MIC50s = 0.025-6.25 µg/ml). Sitafloxacin...

Orbifloxacin is a fluoroquinolone antibiotic used in animals, including dogs, cattle, and swine, to combat gastrointestinal and respiratory infections. It is effective against most Gram-negative bacteria, including Enterobacteriaceae and Pseudomonas, with lower activity against Gram-positive aerobes.Formal Name:...

Enrofloxacin is a fluoroquinolone antibiotic. It is active against panels of Campylobacter, E. coli, and Salmonella isolates (mean MIC50s = 0.06, 0.5, and 0.03 µg/ml, respectively). It is also active against equine isolates of L. intracellularis (MICs = 0.125-0.5 µg/ml). Enrofloxacin inhibits bacterial DNA gyrase....

A fluoroquniolone antibacterial, acts on DNA gyrase.