58 products were found matching "K02091"!
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Palbociclib-d8
Item number: TGM-T12355-1mg
Description: Palbociclib D8 is a deuterium labeled Palbociclib. Palbociclib is a selective and orally active inhibitor of CDK4 and CDK6 (IC50s of 11 and 16 nM, respectively). Smiles: [2H]C1([2H])NC([2H])([2H])C([2H])([2H])N(c2ccc(Nc3ncc4c(C)c(C(C)=O)c(=O)n(C5CCCC5)c4n3)nc2)C1([2H])[2H]. References: Fry DW, et al....
| Keywords: | Palbociclib D8, PD 0332991 D8 |
| Application: | GC-MS, LC-MS, internal standard |
| CAS | 1628752-83-9 |
| MW: | 455.58 D |
From 259.00€
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CDK4/6/1 Inhibitor
Item number: TGM-T10735-100mg
Description: CDK4/6/1 Inhibitor (Crozbaciclib) is a type of CDK4/6 inhibitor (IC50s: 3 and 1 nM). CDK4/6 inhibitor is a class of compounds used for the treatment of some types of hormone receptor positive, HER2-negative breast cancer, which can block the process of breast cancer cell division and reproduction....
| Keywords: | Crozbaciclib |
| Application: | CDK4/6 inhibitor |
| CAS | 2099128-41-1 |
| MW: | 488.57 D |
From 327.00€
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Anti-CDK6 (Ab-13)
Item number: CSB-PA090625.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Keywords: | Anti-CDK6, Anti-CDKN6, EC=2.7.11.22, Anti-Cyclin-dependent kinase 6, Anti-Cell division protein kinase 6,... |
| Application: | ELISA, IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
283.00€
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Anti-CDK6
Item number: CSB-PA245607.100
Host Species: Rabbit. Isotype: IgG. Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific...
| Keywords: | Anti-CDK6, Anti-CDKN6, EC=2.7.11.22, Anti-Cyclin-dependent kinase 6, Anti-Cell division protein kinase 6,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 126.00€
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Anti-Phospho-CDK6 (Tyr24)
Item number: CSB-PA267478.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Keywords: | Anti-phospho-CDK6, Anti-phospho-CDKN6, EC=2.7.11.22, Anti-phospho-Cyclin-dependent kinase 6, Anti-phospho-Cell division... |
| Application: | ELISA, WB, IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
340.00€
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Anti-Phospho-CDK6 (Tyr13)
Item number: CSB-PA549404.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Keywords: | Anti-phospho-CDK6, Anti-phospho-CDKN6, EC=2.7.11.22, Anti-phospho-Cyclin-dependent kinase 6, Anti-phospho-Cell division... |
| Application: | ELISA, WB, IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
340.00€
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Anti-CDK6 (Ab-24)
Item number: CSB-PA564539.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Keywords: | Anti-CDK6, Anti-CDKN6, EC=2.7.11.22, Anti-Cyclin-dependent kinase 6, Anti-Cell division protein kinase 6,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
283.00€
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Anti-CDK6
Item number: CSB-PA871419.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CDK6. Antigen Species: Human
| Keywords: | Anti-CDK6, Anti-CDKN6, EC=2.7.11.22, Anti-Cyclin-dependent kinase 6, Anti-Cell division protein kinase 6,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 167.00€
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LEE011
Item number: Cay17666-10
LEE011 is a cyclin-dependent kinase (CDK) inhibitor that targets cyclin D1/CDK4 and cyclin D3/CDK6 at nanomolar concentrations. It inhibits retinoblastoma protein phosphorylation, which prevents CDK-mediated G1-S phase transition, arresting the cell cycle in the G1 phase, suppressing DNA synthesis, and inhibiting...
| Keywords: | Ribociclib, 7-cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide |
| Application: | Cyclin D1/CDK4 & cyclin D3/CDK6 inhibitor |
| CAS | 1211441-98-3 |
| MW: | 434.5 D |
From 55.00€
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Abemaciclib
Item number: LKT-A044176.5
CDK inhibitor
| Keywords: | LY2835219,... |
| Application: | CDK inhibitor |
| CAS | 1231929-97-7 |
| MW: | 506.61 D |
From 135.00€
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Palbociclib Hydrochloride
Item number: LKT-P0244.5
Palbociclib, also known as PD0332991, is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. PD-0332991 selectively inhibits cyclin-dependent kinases (particularly Cdk4/cyclin D1 kinase), which may inhibit retinoblastoma (Rb) protein...
| Keywords: | PD-033291, PD0332991,... |
| Application: | Cdk4 / Cdk6 inhibitor |
| CAS | 827022-32-2 |
| MW: | 484 D |
From 63.00€
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PD 0332991 (hydrochloride)
Item number: Cay16273-10
PD 0332991 is an orally active, selective inhibitor of the cyclin D kinases Cdk4 (IC50 = 11 nM) and Cdk6 (IC50= 16 nM) with no activity against a panel of 36 additional protein kinases. It has been reported to have antiproliferative activity against retinoblastoma-positive tumor cells, blocking retinoblastoma...
| Keywords: | Palbociclib, 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-pyrido[2,3-d]pyrimidin-7(8H)-one,... |
| Application: | Cyclin-dependent kinase 4/6 (CDK4/6) inhibitor |
| CAS | 827022-32-2 |
| MW: | 484 D |
From 52.00€
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