The following products have been found matching your search "K02090": 61

1 from 6 pages
No results were found for the filter!
NEW
Anti-[KO Validated] CDK5 [Rabbit] (CAB18080)
Anti-[KO Validated] CDK5 [Rabbit] (CAB18080)

Item number: G-CAB18080.20

[KO Validated] CDK5 Rabbit Polyclonal Antibody from Assay Genie with reactivity against Human, Mouse, Rat and for use in WB IF applications.[KO Validated] CDK5 Rabbit Polyclonal Antibody is an IgG isotype antibody and produced in Rabbit and purified by Affinity purification from Assay Genie.. Protein function:...
Keywords: Anti-CDK5, Anti-CDKN5, EC=2.7.11.1, Anti-TPKII catalytic subunit, Anti-Cyclin-dependent-like kinase 5, Anti-Cell division...
Application: WB, IF
Reactivity: Human, Mouse, Rat
From 135.00€ *
Review
NEW
Anti-CDK5 Rabbit (CAB19029)
Anti-CDK5 Rabbit (CAB19029)

Item number: G-CAB19029.20

CDK5 Rabbit Monoclonal Antibody from Assay Genie with reactivity against Human, Mouse, Rat and for use in WB applications.CDK5 Rabbit Monoclonal Antibody is an IgG isotype antibody and produced in Rabbit and purified by Affinity purification from Assay Genie.. Protein function: Proline-directed...
Keywords: Anti-CDK5, Anti-CDKN5, EC=2.7.11.1, Anti-TPKII catalytic subunit, Anti-Cyclin-dependent-like kinase 5, Anti-Cell division...
Application: WB
Reactivity: Human, Mouse, Rat
From 135.00€ *
Review
PNU 112455A
PNU 112455A

Item number: Cay33438-1

PNU 112455A is an inhibitor of cyclin-dependent kinase 2 (Cdk2) and Cdk5 (Ki = 2 µM for both). It inhibits hyperphosphorylation of tau and cell death induced by the synthetic glucocorticoid dexamethasone (Cay-11015) in PC12 rat adrenal medulla cells expressing human tau when used at concentrations of 1 and 10...
Keywords: 4-[(6-amino-4-pyrimidinyl)amino]-benzenesulfonamide, monohydrochloride
Application: Cdk2 / Cdk5 inhibitor
CAS 21886-12-4
MW: 301.8 D
From 35.00€ *
Review
Indirubin
Indirubin

Item number: LKT-I5212.5

Indirubin is a bisindole isomer of indigo, naturally sourced from Indigo naturalis. Indirubin exhibits anti-inflammatory, anti-angiogenic, and anticancer chemotherapeutic activities. In vivo, indirubin decreases levels of IgE and production of inflammatory cytokines, decreasing overall inflammation as well as skin...
Application: CDK inhibitor
CAS 479-41-4
MW: 262.26 D
From 87.00€ *
Review
CDK5 (Phospho-Tyr15) Colorimetric Cell-Based ELISA Kit
CDK5 (Phospho-Tyr15) Colorimetric Cell-Based ELISA Kit

Item number: G-CBCAB00011.96

CDK5 (Phospho-Tyr15) Colorimetric Cell-Based ELISA Kit Protein function: Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and...
Keywords: CDK5, CDKN5, EC=2.7.11.1, TPKII catalytic subunit, Cyclin-dependent-like kinase 5, Cell division protein kinase 5, Tau...
Application: In-cell ELISA
629.00€ *
Review
CDK5 In-Cell ELISA
CDK5 In-Cell ELISA

Item number: G-CBCAB00576.1

Protein function: Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyclins. Phosphorylates SRC, NOS3,...
Keywords: CDK5, CDKN5, EC=2.7.11.1, TPKII catalytic subunit, Cell division protein kinase 5, Cyclin-dependent-like kinase 5, Tau...
Application: In-Cell ELISA
Reactivity: Human, Mouse, Rat
524.00€ *
Review
Dinaciclib
Dinaciclib

Item number: Cay14707-5

Cyclin-dependent kinases (CDKs) are critical positive regulators of cell cycle progression and cellular transcription whose dysregulation can lead to the development of cancer. Dinaciclib inhibits CDK1, CDK2, CDK5, and CDK9 activity in vitro with IC50 values of 3, 1, 1, and 4 nM, respectively. Compared to the...
Keywords: SCH 727965, 1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2S-piperidineethanol
Application: CDK1 / CDK2 / CDK5 / CDK9 inhibitor
CAS 779353-01-4
MW: 396.5 D
From 94.00€ *
Review
SR 1664
SR 1664

Item number: Cay11086-10

Apart from direct peroxisome proliferator-activated receptor gamma (PPARgamma) agonism, several PPARgamma ligands have recently been shown to exert anti-diabetic effects through a second, distinct biochemical function: blocking the obesity-linked phosphorylation of PPARgamma by cyclin-dependent kinase 5 (Cdk5) at...
Keywords: 4'-[[2,3-dimethyl-5-[[[(1S)-1-(4-nitrophenyl)ethyl]amino]carbonyl]-1H-indol-1-yl]methyl]-[1,1'-biphenyl]-2-carboxylic acid
Application: Blocks phosphorylation of PPARgamma by Cdk5
CAS 1338259-05-4
MW: 547.6 D
From 45.00€ *
Review
Butyrolactone I
Butyrolactone I

Item number: BVT-0448-M005

White to off-white solid. Soluble in DMSO, methanol, ethanol or acetone. Isolated from Aspergillus terreus. Cell permeable, potent and selective cyclin-dependent kinase CDK-1 (CDC2), -2 and -5 inhibitor. Apoptosis inducer. Antitumor agent. Inhibits cell cycle progression at the G1/S and G2/M transitions. Shown to...
Application: Cell permeable CDK-1, -2, -5 inhibitor, Apoptosis inducer
CAS 87414-49-1
MW: 424.5 D
From 90.00€ *
Review
PHA-793887
PHA-793887

Item number: Cay18388-5

PHA-793887 is a pyrrolo[3,4-c]pyrazole that inhibits cyclin-dependent kinases Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and Cdk7/cyclin H with IC50 values of 8, 8, 5, and 10 nM, respectively. It is more than 6-fold selective for these kinases over Cdk1/cyclin B, Cdk4/cyclin D1, Cdk9/cyclin T, and GSK3beta (IC50s = 60,...
Keywords: 3-methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]-butanamide
Application: CDK2, CDK5, CDK7 inhibitor
CAS 718630-59-2
MW: 361.5 D
From 44.00€ *
Review
Cdk1/5 Inhibitor
Cdk1/5 Inhibitor

Item number: Cay18740-1

Cyclin-dependent kinases (Cdks) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Cdk1/5 Inhibitor is a pyrazolo [3,4-b] quioxaline that inhibits Cdk1/cyclin B and Cdk5/p25 (IC50s = 600 and 400 nM, respectively). It less potently inhibits GSK3beta (IC50 = 1 µM) and...
Keywords: Cyclin-dependent kinase 1/5 Inhibitor, NSC 693868, 1H-pyrazolo[3,4-b]quinoxalin-3-amine
Application: Cdk1/cyclin B inhibitor, Cdk5/p25 inhibitor
CAS 40254-90-8
MW: 185.2 D
From 49.00€ *
Review
Hymenidin
Hymenidin

Item number: AG-CN2-0503-M001

Amorphous solid. Soluble in DMSO, ethanol or methanol. Inhibitor of CDK5/p25 (IC50=4µ,M) and GSK-3beta (IC50=12µ,M). Potentially useful in neuronal diseases research, Antagonist of serotonergic receptors, Shown to reduce voltage-dependent calcium elevation, Moderate anticancer compound. Inhibits cell...
Keywords: N-[(2E)-3-(2-Amino-1H-imidazol-5-yl)prop-2-en-1-yl]-4-bromo-1H-pyrrole-2-carboxamide, Hymenidine, 2-Debromooroidin
Application: CDK5 inhibitor
CAS 107019-95-4
MW: 328,2 D
198.00€ *
Review
1 from 6 pages