82 products were found matching "K01937"!

Dencatistat is an inhibitor of CTP synthase 1 (CTPS1, IC50 = 0.0093 µM), the enzyme that catalyzes the rate-limiting step in the conversion of UTP to CTP. It is selective for CTPS1 over CTPS2 (IC50 = 12.62 µM). Dencatistat inhibits the proliferation of nine cell lines derived from T cell-based cancers (IC50s = 2-183...

Description: CTPS1 Protein, Mouse, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is P70698.

Description: CTPS2 Protein, Mouse, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is P70303.

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product,...

Protein function: This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP- dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of...

Description: 6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) is a glutaminase antagonist (Ki: 6 µM) and an antineoplastic antibiotic produced by an unidentified Streptomyces species from Peruvian soil. Target: Antibacterial, Antibiotic, Glutaminase, Influenza Virus. Smiles:...

Protein function: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides. [The UniProt Consortium]

6-Diazo-5-oxo-L-nor-Leucine (DON) is a glutamine analog that inhibits glutaminases (Ki = 6 µM) and other glutamine-utilizing enzymes, including cytidine triphosphate synthase (CTPS), which uses glutamine in the synthesis of CTP. DON is commonly used in cells or tissues but its use in whole animals is limited by its...

Protein function: This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP- dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of...

Protein function: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as...

Protein function: This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated...

Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-591aa. Protein Length: Full Length. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: MKYILVTGGV ISGIGKGVIA SSVGTILKSC GLHVTSIKID PYINIDAGTF SPYEHGEVFV LDDGGEVDLD LGNYERFLDI RLTKDNNLTT GKIYQYVINK ERKGDYLGKT VQVVPHITDA IQEWVMRQAL...