36 products were found matching "K01698"!

5-Aminolevulinic acid (5-ALA) is a precursor in the biosynthesis of porphyrins, including heme. The conversion of 5-ALA to protoporphyrins within tissues produces a photosensitive target that produces reactive oxygen species upon exposure to light. In this way, it is used in photodynamic therapy for a range of...

Succinylacetone is an inhibitor of delta-aminolevulinic acid dehydratase (Ki = 300 nM for human erythrocyte enzyme). It inhibits heme biosynthesis and decreases the growth of murine erythroleukemia cells when used at concentrations of 0.1 and 1 mM. Succinylacetone is an abnormal metabolite of tyrosine that...

Protein function: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen. [The UniProt Consortium]

Protein function: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as...

Protein function: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat ALAD. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat ALAD. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ALAD. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ALAD. Next,...

Description: 5-Aminolevulinic acid hydrochloride (5-ALA) is an intermediate in heme biosynthesis and a universal precursor of tetrapyrroles. Target: Endogenous Metabolite, Apoptosis, Autophagy, Mitophagy. Smiles: Cl.NCC(=O)CCC(O)=O. References: Karmakar S, et al. Neurosci Lett,2007, 415(3), 242-247.

Description: 4,6-Dioxoheptanoic acid (Succinylacetone) acts as a potent inhibitor of heme biosynthesis. Target: Endogenous Metabolite, Others. Smiles: CC(=O)CC(=O)CCC(O)=O. References: Ebert PS, et al. Succinylacetone, a potent inhibitor of heme biosynthesis: effect on cell growth, heme contentand...

Aminolevulinate Delta Dehydratase (ALAD) BioAssay(TM) ELISA Kit (Rat) is a sandwich enzyme immunoassay for in vitro quantitative measurement of ALAD in rat serum, erythrocyte lysates and other biological fluids. Detection Range: 0.312-20ng/ml, Sensitivity: 0.128ng/ml, Storage and Stability: Desiccation recommended....

The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway, zinc is essential for enzymatic...