76 products were found matching "K01593"!

Foscarbidopa is a monophosphate prodrug form of the dopamine decarboxylase inhibitor carbidopa (Cay-23783). Formal Name: (alphaS)-alpha-hydrazinyl-3-hydroxy-alpha-methyl-4-(phosphonooxy)-benzenepropanoic acid. CAS Number: 1907685-81-7. Synonyms: ABBV-951. Molecular Formula: C10H15N2O7P. Formula Weight: 306.2....

L-DOPA decarboxylase (DDC) is a pyridoxal 5-phosphate (PLP)-dependent enzyme that catalyzes the decarboxylation of L-DOPA to dopamine and the decarboxylation of L-5HTP to serotonin. DDC is also regarded as a general biomarker for neuroendocrine tumors.

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. DDC antibody detects Aromatic-L-amino-acid decarboxylase, encoded by the DDC gene on chromosome 7p12.2. DDC antibody is widely used in neuroscience, metabolism, and clinical disorder research. DDC, also known as DOPA decarboxylase, catalyzes...

Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare genetic disorder characterized by deficient synthesis of dopamine and serotonin. It presents in early infancy, and causes severe developmental disability and lifelong motor, behavioral, and autonomic symptoms including oculogyric crises (OGC), sleep...

Carbidopa is a peripherally restricted inhibitor of dopamine decarboxylase, the enzyme that converts L-DOPA (Cay-13248) to dopamine. Carbidopa (100 mg/kg) pretreatment in dog increases the plasma concentration of L-DOPA by 186% and prolongs the half-life in plasma by 48% and skeletal muscle extracellular fluid by...

Benserazide is a peripherally restricted inhibitor of aromatic L-amino acid decarboxylase (AADC, IC50 = 0.53 µM). It also inhibits tryptophan oxygenase and kynureninase (Kis = 41.8 and 26.4 µM, respectively, in rat liver homogenates), as well as hexokinase 2 (HK2), HK1, and HK4 (IC50s = 5.5, 25.1, and 40.5 µM,...

L-(-)-alpha-Methyldopa is a dopamine (DOPA) decarboxylase inhibitor (ED50 = 21.8 mg/kg) and has antihypertensive activity in vitro and in vivo. L-(-)-alpha-Methyldopa enters the CNS and is metabolized to form alpha-methylnorepinephrine which acts as an agonist at alpha2-adrenergic receptors. Formulations containing...

L-DOPA (Cay-13248) is a metabolic precursor of dopamine that is capable of crossing the blood brain barrier to act as a dopamine D1 receptor agonist. It is produced from L-tyrosine by trysosine hydroxylase. In the brain, L-DOPA is converted to dopamine by the enzyme aromatic L-amino acid decarboxylase. It is...

Protein function: Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to...

Protein function: Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. [The UniProt Consortium]

Anti-DOPA Decarboxylase antibody is directed against rat DOPA Decarboxylase. Anti-DOPA Decarboxylase antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Anti-DOPA Decarboxylase antibody recognizes DOPA Decarboxylase from bovine and rat sources. Cross reactivity with DOPA...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: DDC, aromatic L-amino acid decarboxylase (AADC) Protein function: Catalyzes the decarboxylation of L-3,4- dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and...