82 products were found matching "K01539"!

Ouabain-d3 is intended for use as an internal standard for the quantification of ouabain by GC- or LC-MS. Ouabain is a cardiac glycoside that has been found in S. gratus and has diverse biological activities. It inhibits the Na+/K+-ATPase isoforms alpha1beta1 and alpha2beta1 and human-ether-a-go-go (hERG), also...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rabbit ATP1a1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rabbit ATP1a1....

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ATP1a1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ATP1a1....

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ATP1a2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ATP1a2....

Marinobufagenin (MBG) is a bufadienolide steroid first isolated from toads of genus Bufo. It can also be excreted by mammalian cells, particularly kidney cells from hypertensive animals. MBG inhibits the ouabain-resistant alpha1 Na+/K+ ATPase subunit (IC50 = 78 nM), impairing a major sodium pump of the kidneys,...

Acetyldigitoxin is cardiac glycoside and an inhibitor of the Na+/K+ ATPase with an IC50 value of 5 nM in isolated rat pinealocytes. This inhibition results in loss of the transmembrane Na+ gradient, which decreases activity of the Na+/Ca2+ exchanger, increasing intracellular calcium levels, inotropy, and cardiac...

Bretylium is a class III antiarrhythmic agent and an inhibitor of the Na+/K+-ATPase (IC50 = 4.5 mM). Bretylium also has antiadrenergic activity, inhibiting auricular nerve stimulation-induced vasoconstriction in isolated rabbit ears and hypogastric nerve stimulation-induced contraction of isolated rabbit uterus. It...

Deslanoside is a cardiac glycoside that has been found in D. lanata. It induces ventricular tachycardia in anesthetized dogs when administered intravenously at a dose of 0.18 mg/kg. Formulations containing deslanoside have been used in the treatment of congestive heart failure and cardiac arrythmias.Formal Name:...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na...

Protein function: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of...

This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients....

Digoxigenin monodigitoxoside is a Na+/K+-ATPase inhibitor and cardiac glycoside metabolite of digoxin (Cay-22266). It has a binding affinity of 0.829 and an inhibitory potency of 1.07 relative to [3H]ouabain in a competitive binding assay using purified lamb Na+/K+-ATPase and for its ATPase activity, respectively....