61 products were found matching "K01522"!

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Bis(5'-adenosyl)-triphosphatase, also known as fragile histidine triad protein (FHIT) is an enzyme that in humans is encoded by the FHIT gene. This gene, a member of the histidine triad gene family, encodes a diadenosine P1,P3-bis(5'-adenosyl)-triphosphate...

This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 0, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In...

Cayman's FHIT Fluorometric Activity Assay Kit provides a convenient method of detecting FHIT activity in cell and tissue lysates. Measurement of the FHIT activity is carried out by monitoring the hydrolysis of an FHIT substrate analog, TG-1AdaAMP, generating free Tokyo Green(TM), whose fluorescence can be easily...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Bis(5'-adenosyl)-triphosphatase, also known as fragile histidine triad protein (FHIT) is an enzyme that in humans is encoded by the FHIT gene. This gene, a member of the histidine triad gene family, encodes a diadenosine P1,P3-bis(5'-adenosyl)-triphosphate...

Protein function: Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'- adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes...

This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In...

Protein function: Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'- adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes...

This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In...

8Br-HA is an inhibitor of fragile histidine triad diadenosine triphosphatase (FHIT, IC50 = 0.12 µM). It inhibits the growth of HCC827 and H460 lung cancer cells (GI50s = 0.87 and 5.9 µM, respectively).Formal Name: 2-((4-bromo-6-oxo-7,8,9,10-tetrahydro-6H-benzo[c]chromen-3-yl)oxy)-N-hydroxyacetamide. CAS Number:...

Protein function: Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes...

Protein function: Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes...

Fragile histidine triad diadenosine triphosphatase (FHIT) is a hydrolase and tumor suppressor. It contains a His-x-His-x-His motif that hydrolyzes diadenosine triphosphate (Ap3A), as well as Ap4A and ATP. FHIT is expressed in spleen, brain, kidney, lung, and liver and localizes to the plasma membrane, nucleus,...