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CB-839
CB-839

Item number: Cay22038-1

CB-839 is an orally bioavailable noncompetitive inhibitor of the glutaminase 1 (GLS1) splice variants, kidney-type (KGA) and glutaminase C (GAC), which convert glutamine into glutamate. CB-839 inhibits human recombinant GAC with IC50 values of less than 50 nM, varying based on the length of preincubation. It...
Keywords: GLS1 Inhibitor III,...
Application: Glutaminase inhibitor
CAS 1439399-58-2
MW: 571.6 D
From 38.00€ *
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BPTES
BPTES

Item number: Cay19284-1

BPTES is an allosteric inhibitor of kidney-type glutaminase 1 (GLS1, IC50 = 3.3 µM) that drives the formation of inactive GLS1 tetramers. It is selective for GLS1 over GLS2, glutamate dehydrogenase, and gamma-glutamyl transpeptidase. BPTES decreases glutaminase activity and reduces proliferation of aerobic P493...
Keywords: N,N'-[thiobis(2,1-ethanediyl-1,3,4-thiadiazole-5,2-diyl)]bis-benzeneacetamide
Application: GLS inhibitor
CAS 314045-39-1
MW: 524.7 D
From 32.00€ *
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Anti-Glutaminase
Anti-Glutaminase

Item number: ARG41936.100

Protein function: Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate, the main excitatory neurotransmitter in the brain (PubMed:30575854, PubMed:30239721,...
Keywords: Anti-GLS, Anti-GLS1
Application: FC, ICC, IF, IHC (paraffin), WB
Reactivity: Human
483.00€ *
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Anti-Glutaminase (KGA)
Anti-Glutaminase (KGA)

Item number: ARG41939.100

Protein function: Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate, the main excitatory neurotransmitter in the brain (PubMed:30575854, PubMed:30239721,...
Keywords: Anti-GLS, Anti-GLS1
Application: IHC (paraffin), WB
Reactivity: Human, Mouse
483.00€ *
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Glutaminase Inhibitor Compound 968
Glutaminase Inhibitor Compound 968

Item number: Cay17199-25

Glutaminase inhibitor compound 968 is a cell-permeable, reversible inhibitor of a mitochrondrial glutaminase splice variant, glutaminase C (IC50 = ~2.5 µM), which is commonly found in cancer cells. Through this action, glutaminase inhibitor compound 968 blocks transformation induced by Rho GTPases and inhibits the...
Keywords: 5-[3-bromo-4-(dimethylamino)phenyl]-2,3,5,6-tetrahydro-2,2-dimethyl-benzo[a]phenanthridin-4(1H)-one
Application: Glutaminase inhibitor
CAS 311795-38-7
MW: 475.4 D
From 32.00€ *
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BPTES
BPTES

Item number: AG-CR1-3690-M005

Keywords: Bis-2-(5-phenylacetamido-1,3,4-thiadiazol-2-yl)ethyl sulfide
Application: Selective, allosteric non-competitive glutaminase 1 (GLS1) inhibitor
CAS 314045-39-1
MW: 524.7 D
From 33.00€ *
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GLS1 Inhibitor
GLS1 Inhibitor

Item number: Cay28581-1

GLS1 inhibitor is an inhibitor of glutaminase 1 (GLS1, IC50 = 0.021 µM). It inhibits the growth of NCI H1703 non-small cell lung cancer (NSCLC) cells in vitro (GI50 = 0.011 µM). GLS1 inhibitor (100 mg/kg) reduces tumor growth, increases tumor levels of glutamine, and decreases tumor levels of glutamate and aspartate...
Keywords: alphaS-methoxy-N-[5-[[(3R)-1-(3-pyridazinyl)-3-pyrrolidinyl]amino]-1,3,4-thiadiazol-2-yl]-benzeneacetamide
Application: K-glutaminase inhibitor
CAS 1832646-52-2
MW: 4115 D
From 32.00€ *
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Human GLS / Glutaminase kidney isoform, mitochondrial ELISA Kit
Human GLS / Glutaminase kidney isoform, mitochondrial...

Item number: G-HUFI01447.96

Application: ELISA
Reactivity: Human
629.00€ *
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Human Glycated Albumin ELISA Kit
Human Glycated Albumin ELISA Kit

Item number: G-HUFI02480.96

Application: ELISA
Reactivity: Human
629.00€ *
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Anti-GLS2
Anti-GLS2

Item number: 600-401-BL8

Anti-GLS2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. GLS2 antibody is predicted to not cross-react with other catenin family members. Multiple isoforms of GLS2 are known to exist. Protein function: Plays an important role in the regulation of glutamine catabolism....
Keywords: Anti-GA, Anti-GLS, Anti-GLS2, EC=3.5.1.2, Anti-L-glutaminase, Anti-L-glutamine amidohydrolase, Anti-Glutaminase liver...
Application: ELISA, IHC, IF, WB
Reactivity: Human, Mouse, Rat
493.00€ *
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Anti-Glutaminase
Anti-Glutaminase

Item number: ARG55696.100

Protein function: Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. [The UniProt Consortium]
Keywords: Anti-GLS, Anti-GLS1, EC=3.5.1.2, Anti-K-glutaminase, Anti-L-glutamine amidohydrolase, Anti-Glutaminase kidney isoform,...
Application: WB, IHC (paraffin), ICC, IF, FC
Reactivity: Human, Mouse, Rat
452.00€ *
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Anti-GLS2
Anti-GLS2

Item number: ARG55842.100

Protein function: Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role...
Keywords: Anti-GA, Anti-GLS, Anti-GLS2, EC=3.5.1.2, Anti-L-glutaminase, Anti-L-glutamine amidohydrolase, Anti-Glutaminase liver...
Application: IHC (paraffin), WB
Reactivity: Human, Mouse
452.00€ *
Review
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