266 products were found matching "K01403"!

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Mmp9, or matrix metalloproteinase nine, is a zinc dependent endopeptidase that plays a central role in extracellular matrix remodeling during development, inflammation, and tissue repair. In zebrafish, Mmp9 is involved in multiple biological processes including...

Protein function: Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. [The UniProt Consortium]

The Fluorogenic MMP9 (Q279R) Assay Kit is designed to measure MMP9 (Q279R) activity for screening and profiling applications, in a homogeneous assay with no time-consuming washing steps.

GM 6001 is a potent, reversible broad spectrum inhibitor of zinc-containing proteases, including matrix metalloproteinases (MMPs). It inhibits zinc-containing thermolysin and elastase from P. aeruginosa, both with Ki values of 20 nM. GM 6001 inhibits MMP-1, -2, -7, -8, -9, -12, -13, -14, -16, and -26 with Ki or IC50...

MMP-2/MMP-9 inhibitor II is a dual inhibitor of matrix metalloproteinase-2 (MMP-2) and MMP-9 (IC50s = 17 and 30 nM, respectively). In mice, it suppresses lung colonization of Lewis lung carcinoma cells and inhibits tumor-induced angiogenesis, tumor growth, and liver metastasis.,Formal Name:...

Doxycycline is a synthetic teracycline. Inhibits angiogenesis in a quantitative in vitro assay of angiogenesis. Inhibits proliferation of the human leukemia cell line K562. It reduces lung metastases by inhibiting the secretion and acitivity of marrix metalloproteinases (MMPs).

NF-kappaB activation inhibitor III is an inhibitor of NF-kappaB activation. NF-kappaB activation inhibitor III (20 µM) inhibits TNF-alpha-induced NF-kappaB activation in HT-1080 fibrosarcoma cells. NF-kappaB activation inhibitor III inhibits TNF-alpha-induced expression of the gene encoding matrix...

MMP-2/MMP-9 inhibitor I is a potent inhibitor of matrix metalloproteinase-2 (MMP-2) and MMP-9 (IC50s = 310 and 240 nM, respectively). It acts by binding zinc at the active site of these MMPs. MMP-2/MMP-9 inhibitor I is active in vivo as well as in vitro and blocks MMP-2/MMP-9-dependent invasion, tumor growth, and...

Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. MMP Inhibitor II is a reversible, broad-range inhibitor of MMPs. It has been reported to inhibit MMP-1 (IC50 = 24 nM), MMP-3...

ND-336 is a selective inhibitor of the gelatinases matrix metalloproteinase-2 (MMP-2) and MMP-9, as well as MMP-14 (Kis = 85, 150, and 120 nM, respectively). It has minimal effect on other MMPs. ND-336 accelerates diabetic wound healing in mice by lowering inflammation and by enhancing angiogenesis and...

MMP-9/MMP-13 inhibitor I is a cell-permeable inhibitor of matrix metalloproteinases (MMPs) that most potently inhibits MMP-9 and MMP-13 (IC50s = 0.9 nM for both). It less effectively inhibits MMP-1, MMP-3, and MMP-7 (IC50s = 43, 23, and 920 nM, respectively). MMP-9/MMP-13 inhibitor I has been used to elucidate the...

SB-3CT is a selective, mechanism-based inhibitor of the gelatinases, matrix metalloproteinase-2 (MMP-2) and MMP-9 (Kis = 28 and 400 nM, respectively). First pass metabolism of SB-3CT in vivo produces a monohydroxylated metabolite that has greater inhibitory activity (Kis = 6 and 160 nM for MMP-2 and MMP-9,...