151 products were found matching "K01370"!

Recognizes endogenous full-length and activated (p20 fragment) mouse caspase-1. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response...

Recognizes endogenous full-length and activated (p20 fragment) human caspase-1. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic Caspase-1 is the best-described inflammatory caspase. It...

Kit includes 660-YVAD-FMK red caspase-1 probe, 10x Apoptosis Wash Buffer, Fixative, Technical Protocol. The red FLICA® 660-YVAD-FMK caspase-1 detection probe is comprised of the preferred affinity peptide sequence for active caspase-1 (YVAD), a far-red fluorescent 660 dye label, and a fluoromethyl ketone (FMK)...

This kits makes use of a cell-permeant green fluorecent probe (FAM-YVAD-FMK) that binds to active caspase-1 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.

This kits makes use of a cell-permeant green fluorecent probe (FAM-YVAD-FMK) that binds to active caspase-1 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.

CASP1(caspase 1) Homo sapiens This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved...

Detection Type: Colorimetric. Assay Type: Sandwich 96 well assay. Sample Type: Cell Culture Supernatant. Range: 0.15ng/ml to 10ng/ml. Sensitivity: 33pg/ml. Detects mouse caspase-1 (proform as well as p10 and p20 domain). Does not detect human caspase-1. Caspase-1 is the best-described inflammatory caspase. It...

Emricasan is a pan-caspase inhibitor. Ex vivo, emricasan (10 mg/kg) prevents cold ischemia-warm reperfusion-induced sinusoidal endothelial cell (SEC) apoptosis and inhibits caspase-3 activation in rat liver by 55 and 94%, respectively. In vivo, emricasan reduces alanine aminotransferase (ALT) levels (ED50s = 95%....

ICT's Pyroptosis/Caspase-1 Assay, Far Red utilizes our popular FLICA technology to measure caspase-1 activation. Using this kit, researchers can easily detect pyroptotic cells in their whole cell samples in vitro. This complete kit includes Nigericin for the simple and reliable generation of a positive control....

Molecular weight: 854.84. Excitation (nm): 493. Emission (nm): 517. Extinction coefficient (cm-1 M-1): 83000. Correction factor (280 nm): 0.178. Correction factor (260 nm): 0.32. FAM-YVAD-FMK, i.e., 5-carboxyfluorescein-Tyr-Val-Ala-Asp-fluoromethylketone, binds irreversibly to active caspase 1 in stimulated cells....

Recognizes endogenous full-length and activated (p20 fragment) human caspase-1. Liquid. Purified from concentrated hybridoma tissue culture supernatant. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1...

Ac-YVAD-CHO is an inhibitor of caspase-1/interleukin-1beta converting enzyme (ICE, Ki = 0.76 nM) and an acetylated form of the caspase-1 inhibitor YVAD-CHO (Cay-27420). It is selective for caspase-1 over caspase-4, -5, -8, -9, and -10 (Kis = 163-970 nM), as well as over caspase-2, -3, -6, and -7 (Kis = >10,000 nM...