92 products were found matching "K01367"!

Protein function: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction (PubMed:19617626, PubMed:21531719, PubMed:2400579). Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His-409' (PubMed:23707407)....

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse CAPN1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse CAPN1. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CAPN1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CAPN1. Next,...

Formulation: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. Cellular Localization: Cell membrane, Cytoplasm. Positive Control: HeLa cells. Skin or Tonsil. Chromosome Location: 11q13.1. Protein Function: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in...

Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Cell membrane, Cytoplasm. Positive Control: HeLa cells. Skin or Tonsil. Chromosome Location: 11q13.1. Protein Function: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in...

The calpains are a family of calcium-dependent cysteine proteases which catalyze limited proteolysis of substrates. PD 150606 is a selective, cell-permeable inhibitor of calpains (Ki = 0.21 µM for µ-calpain (calpain-1) and 0.37 µM for m-calpain (calpain-2)). PD 150606 is commonly used to elucidate the roles for...

The calpains are a family of calcium-dependent cysteine proteases that catalyze limited proteolysis of substrates. Calpain Inhibitor III is a cell permeable, selective inhibitor of µ-calpain (calpain-1) and m-calpain (calpain-2). Calpain Inhibitor III crosses the blood-brain barrier to inhibit brain cysteine...

Calpain inhibitor II is a cell permeable, peptide aldehyde inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 0.6 nM). It has been used to demonstrate the involvement of ubiquitin-proteasome protein degradation in various biological systems.Formal Name:...

Calpain inhibitor XII is a reversible and selective inhibitor of calpain I (µ-calpain, Ki = 19 nM), with lower affinities for calpain II (m-calpain, Ki = 120 nM) and cathepsin B (Ki = 750 nM). Calpain inhibitors, including this compound, have been used to study the role of calpains in diverse processes, including...

Calpain inhibitor VI is an inhibitor of the calcium-dependent cysteine proteases µ-calpain (calpain-1, IC50 = 7.5 nM) and m-calpain (calpain-2, IC50 = 78 nM). It also inhibits cathepsins B and L (IC50s = 15 and 1.6 nM, respectively). It is selective for these calpains and cathepsins over other cysteine and serine...

The calpains are a family of calcium-dependent cysteine proteases, with calpain I (µ-calpain) requiring micromolar calcium and calpain II (m-calpain) requiring millimolar calcium. Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain (another cysteine protease) that is used for measuring the...

Description: Aureusimine B, a Calpain inhibitor, is produced by Staphylococcus aureus biofilms and could be a potential biomarker for S. aureus biofilm-based infections. Target: Cysteine Protease, Antibacterial. Smiles: CC(C)c1ncc(Cc2ccccc2)[nH]c1=O