39 products were found matching "K01322"!

KYP-2047 is an inhibitor of prolyl endopeptidase (Ki = 0.02 nM for the porcine enzyme). It inhibits hydrogen peroxide-induced aggregation of alpha-synuclein in SH-SY5Y cells expressing wild-type, alpha-synucleinA30P, or alpha-synucleinA53T in in vitro models of Parkinson's disease when used at a concentration of 1...

HUP-55 is an inhibitor of prolyl endopeptidase (IC50 = 5 nM). It reduces alpha-synuclein dimerization in Neuro2a cells, induces autophagy in HEK293 cells, and decreases hydrogen peroxide-induced increases in reactive oxygen species (ROS) production in SH-SY5Y cells when used at a concentration of 10 µM. HUP-55 (10...

Active human Prolyl oligopeptidase (POP)/Prolyl endopeptidase (PREP) (GenBank Accession No. NM_002726.) full length with N-terminal His tag, MW = 81.6 kDa, expressed in an E. coli expression system.

Z-Gly-Pro-AMC is a fluorogenic substrate for the determination of post-proline cleaving enzyme (prolyl endopeptidase).

The Fluorogenic Prolyl OligoPeptidase (POP) Assay Kit is a complete assay system designed to measure activity of the purified POP enzyme. It comes in a convenient 96-well format, with all the reagents necessary for 100 reactions. The Fluorescent POP Activity Assay eliminates the dealing with radioactive materials...

Phytotoxic, antifungal and antihelmintic, Prolylendopeptidase inhibitor. Isolated from Phoma sp.

Protein function: Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. [The UniProt Consortium]

Protein function: Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. [The UniProt Consortium]

Berberine is an isoquinoline alkaloid found in a variety of plants, including barberry, goldenseal, Oregon grape, California poppy, and the Amur cork tree. Berberine fluoresces under ultraviolet light and is often used to stain heparin in mast cells. Like many other natural products, berberine displays many...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: PREP Protein function: Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. [The UniProt Consortium]

Isolated from Streptomyces sp. Antibiotic. 14-Membered macrolide. Active against Gram-positive bacteria including mycobacteria. Prolyl endopeptidase (PREP) inhibitor.

(S)-Laudanosine is the (S) enantiomer of laudanosine, a metabolite of the neuromuscular blocking agents atracurium (Cay-17796) and cisatracurium (Cay-22959). (S)-Laudanosine is also an alkaloid that has been found in the prickly poppy A. platyceras. It inhibits prolyl endopeptidase with an IC50 value of 341 µM....