88 products were found matching "K01315"!

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Plasminogen (PLG) is a circulating zymogen that is converted to the active enzyme plasmin by cleavage of the peptide bond between arg560 and val561, which is mediated by urokinase (PLAU) and tissue plasminogen activator (PLAT). The main function of plasmin is to...

D-Val-Leu-Lys-AMC (vLK-AMC) is a fluorogenic substrate for plasmin. Upon enzymatic cleavage by plasmin, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify plasmin activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively. vLK-AMC has been used to...

Tranexamic acid is an inhibitor of fibrinolysis that inhibits the interaction of plasmin with fibrin (IC50 = 3.1 µM in isolated human plasma). It decreases alpha-naphthylisothiocyanate (ANIT)-induced increases in the expression of the profibrogenic genes Timp1 and Col1a1, but not Itgb6, Tgfbeta1, or Tgfbeta2, and...

6-Aminocaproic acid is an inhibitor of the plasmin activating enzymes streptokinase, fibrinokinase, and urokinase (IC50s = ~8 µM for all in an enzyme assay). It is selective for plasmin activating enzymes over trypsin (IC50 = >500 µM). 6-Aminocaproic acid inhibits in vitro plasmin activation and fibrinolysis in a...

Anti-Plasminogen is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.  Assay by immunoelectrophoresis resulted in a single precipitin arc...

D-VLK-AMC is a sensitive, highly specific fluorescent substrate for plasmin. It can be used with a fluorescence microscope, fluorescence microplate or flow cytometer.

Anti-PLASMINOGEN is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.  Assay by immunoelectrophoresis resulted in a single precipitin arc...

Anti-Plasminogen antibody is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.  Assay by immunoelectrophoresis resulted in a single...

Plasminogen inhibitor.

Protein function: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen...

Anti-PLASMINOGEN is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.  Assay by immunoelectrophoresis resulted in a single precipitin arc...