95 products were found matching "K01314"!

Rabbit Polyclonal F10 Antibody against Human coagulation factor X. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000031444: 88%, ENSRNOG00000033444: 82%....

Apixaban is an orally bioavailable, selective inhibitor of both free and prothrombinase-bound factor Xa (Kis = 0.8 nM). In vivo, apixaban has antithrombotic effects in a rabbit model of venous thrombosis. Apixaban (357.5 mg) also prevents thrombus formation without inducing adverse bleeding events in a porcine model...

Rivaroxaban is an orally active, direct inhibitor of Factor Xa (Ki = 0.4 nM), which is a crucial component of the intrinsic and extrinsic pathways of the blood coagulation cascade. It demonstrates >10,000-fold greater selectivity for Factor Xa compared to other related serine proteases. In various animal arterial...

An oral anticoagulant.

Edoxaban is an orally bioavailable and potent inhibitor of factor Xa (Kis = 0.561 and 0.903 nM for free and complexed human factor Xa, respectively). It is >10,000-fold selective for factor Xa over thrombin, FVIIa/sTF, FXIa, tPA, aPC, trypsin, plasmin, and chymotrypsin. Edoxaban prolongs prothrombin, activated...

Apixaban-13C-d3 is intended for use as an internal standard for the quantification of apixaban (Cay-15427) by GC- or LC-MS. Apixaban is an orally bioavailable, selective inhibitor of both free and prothrombinase-bound factor Xa (Kis = 0.8 nM). In vivo, apixaban has antithrombotic effects in a rabbit model of venous...

Rivaroxaban-d4 is intended for use as an internal standard for the quantification of rivaroxaban (Cay-16043) by GC- or LC-MS. Rivaroxaban is an orally active, direct inhibitor of Factor Xa (Ki = 0.4 nM), which is a crucial component of the intrinsic and extrinsic pathways of the blood coagulation cascade. It...

Bz-IEGR-pNA is a colorimetric substrate for Factor Xa. Factor Xa preferentially binds to and cleaves the Ile-Glu-Gly-Arg (IEGR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity.Formal Name:...

Description: Eribaxaban (PD348292) is an orally available factor Xa inhibitor for the prevention and treatment of venous thromboembolism. Target: Factor Xa. Smiles: C(NC1=C(F)C=C(C=C1)N2C(=O)C=CC=C2)(=O)[C@@H]3N(C(NC4=CC=C(Cl)C=C4)=O)C[C@H](OC)C3. References: Bondarenko M,et al. Efficacy and toxicity of factor Xa...

Protein function: Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. [The UniProt Consortium]

Betrixaban is an inhibitor of the serine protease Factor Xa (Ki = 0.117 nM, IC50 = 1.5 nM), the enzyme that activates prothrombin in the blood coagulation cascade. It is selective for Factor Xa over hERG channels (Ki = 1.8 µM, IC50 = 8.9 µM), indicating a low potential for adverse cardiac effects. In vitro,...