21 products were found matching "K01131"!

3-Formylsalicylic acid is a non-competitive inhibitor of estrone sulfatase (IC50 = 150 nM, Ki = 120 nM), the enzyme that converts estrone sulfate to estrone. 3-Formylsalicylic acid has been used in the synthesis of Schiff bases.Formal Name: 3-formyl-2-hydroxy-benzoic acid. CAS Number: 610-04-8. Synonyms: NSC 55753....

Protein function: Conversion of sulfated steroid precursors to estrogens during pregnancy. [The UniProt Consortium]

Inhibits steroid sulfatase. Enhances learning and spatial memory in rats. Inhibits proliferation of human MCF-7 breast cancer cells.

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Steryl-sulfate sulfohydrolase, STS Protein function: Conversion of sulfated steroid precursors to estrogens during pregnancy. [The UniProt Consortium]

STX140 is an estrogen sulfamate with anticancer activities. It inhibits steroid sulfatase with IC50 values of 39 and 0.5 nM in placental microsomes and MCF-7 cancer cells, respectively. STX140 also binds to carbonic anhydrase IX and II (Kis = 70 and 270 nM, respectively). It inhibits bovine brain tubulin assembly in...

STX-64 is a steroid sulfatase inhibitor (IC50 = 0.008 µM in placental microsomes). It also inhibits carbonic anhydrase II (CAII, IC50 = 0.025 µM). STX-64 inhibits LPS-induced production of nitric oxide (NO) and prostaglandin E2 (PGE2, Cay-14010) in RAW 264.7 macrophages (IC50s = 85.76 and 0.081 µM, respectively). It...

Protein function: Catalyzes the conversion of sulfated steroid precursors, such as dehydroepiandrosterone sulfate (DHEA-S) and estrone sulfate to the free steroid. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse:...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Steroid sulfatase (STS), or steryl-sulfatase, formerly known as arylsulfatase C, is a sulfatase enzyme involved in the metabolism of steroids. It is encoded by the STS gene. This gene encodes a multi-pass membrane protein that is localized to the endoplasmic...

Description: Irosustat (667-Coumate) is a potent steroid sulfatase inhibitor, with an IC50 of 8 nM, and exhibits anti-breast cancer activity. Target: Others. Smiles: NS(=O)(=O)Oc1ccc2c3CCCCCc3c(=O)oc2c1. References: Raobaikady B,etal.Inhibition of MCF-7 breast cancer cell proliferation and in vivo steroid sulphatase...

STS Antibody is a premium polyclonal that offers outstanding performance and reliability for demanding research applications. Rigorously validated for ELISA, WB, IHC, this antibody ensures consistent, reproducible results across multiple experimental platforms. Demonstrates excellent reactivity with Human, Mouse,...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....