22 products were found matching "K01131"!

DU-14 is a steroid sulfatase inhibitor (IC50 = 55.8 nM). It inhibits the proliferation of MCF-7 breast cancer cells (IC50 = 38.7 nM). In vivo, DU-14 (30 mg/kg), in combination with the steroid precursor dehydroepiandrosterone sulfate (DHEAS, Cay-15873), potentiates DHEAS reversal of scopolamine-induced amnesia in...

3-Formylsalicylic acid is a non-competitive inhibitor of estrone sulfatase (IC50 = 150 nM, Ki = 120 nM), the enzyme that converts estrone sulfate to estrone. 3-Formylsalicylic acid has been used in the synthesis of Schiff bases.Formal Name: 3-formyl-2-hydroxy-benzoic acid. CAS Number: 610-04-8. Synonyms: NSC 55753....

Protein function: Conversion of sulfated steroid precursors to estrogens during pregnancy. [The UniProt Consortium]

Inhibits steroid sulfatase. Enhances learning and spatial memory in rats. Inhibits proliferation of human MCF-7 breast cancer cells.

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Steryl-sulfate sulfohydrolase, STS Protein function: Conversion of sulfated steroid precursors to estrogens during pregnancy. [The UniProt Consortium]

STX140 is an estrogen sulfamate with anticancer activities. It inhibits steroid sulfatase with IC50 values of 39 and 0.5 nM in placental microsomes and MCF-7 cancer cells, respectively. STX140 also binds to carbonic anhydrase IX and II (Kis = 70 and 270 nM, respectively). It inhibits bovine brain tubulin assembly in...

STX-64 is a steroid sulfatase inhibitor (IC50 = 0.008 µM in placental microsomes). It also inhibits carbonic anhydrase II (CAII, IC50 = 0.025 µM). STX-64 inhibits LPS-induced production of nitric oxide (NO) and prostaglandin E2 (PGE2, Cay-14010) in RAW 264.7 macrophages (IC50s = 85.76 and 0.081 µM, respectively). It...

Protein function: Catalyzes the conversion of sulfated steroid precursors, such as dehydroepiandrosterone sulfate (DHEA-S) and estrone sulfate to the free steroid. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse:...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Steroid sulfatase (STS), or steryl-sulfatase, formerly known as arylsulfatase C, is a sulfatase enzyme involved in the metabolism of steroids. It is encoded by the STS gene. This gene encodes a multi-pass membrane protein that is localized to the endoplasmic...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....