118 products were found matching "K01062"!

Platelet-activating factor (PAF) is a biologically active phospholipid synthesized by a variety of cells upon stimulation. PAF is converted to the biologically inactive lyso-PAF by the enzyme PAF acetylhydrolase (PAF-AH). Plasma PAF-AH is highly selective for phospholipids with very short acyl groups at the sn-2...

Lipoprotein-associated phospholipase A2 (LpPLA2) is an enzyme which participates in proinflammatory process. High concentration of LpPLA2 in serum indicates risk of heart attack and stroke. LpPLA2 is considered as specific coronary marker for diagnosing cardiovascular heart disease.

Lipoprotein-associated phospholipase A2 (LpPLA2) is an enzyme which participates in proinflammatory process. High concentration of LpPLA2 in serum indicates risk of heart attack and stroke. LpPLA2 is considered as specific coronary marker for diagnosing cardiovascular heart disease.

Endogenous PLA2G7 transcription levels were found to be significantly lower in vascular related cell lines than in the other cell lines. Luciferase reporter gene assays indicated that gene activity was significantly enhanced by PLA2G7 promoter fragment. LA2G7 transcription was found to be up-regulated with the...

Endogenous PLA2G7 transcription levels were found to be significantly lower in vascular related cell lines than in the other cell lines. Luciferase reporter gene assays indicated that gene activity was significantly enhanced by PLA2G7 promoter fragment. LA2G7 transcription was found to be up-regulated with the...

Rilapladib is an inhibitor of platelet-activating factor acetylhydrolase (PAF-AH), also known as lipoprotein-associated phospholipase A2 (Lp-PLA2, IC50 = 230 pM). InChI:...

Lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as platelet activating factor acetylhydrolase (PAF-AH) or phospholipase A2 group 7 (PLA2G7), hydrolyzes glycerophospholipids to produce lyso-PAF/lyso-phosphatidylcholine and short and/or oxidized fatty acids, many of which have pro-inflammatory or...

Platelet-activating factor (PAF) is an important lipid mediator involved in inflammation. PAF-acetylhydrolase (PAF-AH) is an extracellular phospholipase A2 which hydrolyzes the acetyl group at the sn-2 position of phospholipids. Two main types of PAF-AH have been characterized, namely the secreted (i.e. plasma) and...

Lipoprotein-associated phospholipase A2, also known as platelet activating factor acetylhydrolase (PAF-AH) or phospholipase A2 group 7, hydrolyzes glycerophospholipids to produce lyso-PAF/lyso-phosphatidylcholine and short and/or oxidized fatty acids, many of which have pro-inflammatory or pro-oxidative activities....

Platelet-activating factor acetylhydrolase (PAF-AH) is a calcium-independent member of the phospholipase A2 (PLA2) family that hydrolyzes the acetyl group at the sn-2 position of PAF, a phospholipid mediator involved in a variety of biological activities. There are three types of PAF-AH: two intracellular forms,...

Human PLA2G7, (GenBank Accession No. NM_005084), (amino acids 22-441(end)), with C-terminal His-tag, MW=49.2 kDa, expressed in a mammalian cell expression system. Assay Conditions: Enzyme reaction is conducted using liposomally incorporated Red/Green BODIPY PC-A2 (5 ?M, Invitrogen) as a substrate in a reaction...

This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader...