51 products were found matching "K00921"!
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YM-201636
Item number: Cay13576-1
PIKfyve is a phosphoinositide kinase (PIK) that contains a FYVE-type zinc finger domain, which binds phosphatidylinositol 3-phosphate (PI3P). PIKfyve phosphorylates PI3P to produce PI-(3,5)-P2, which is involved in cellular processes including membrane trafficking and cytoskeletal reorganization. YM-201636 is a...
| Keywords: | 6-amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide |
| Application: | PIKfyve inhibitor |
| CAS | 371942-69-7 |
| MW: | 467.5 D |
From 75.00€
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APY0201
Item number: Cay9001589-1
APY0201 is an inhibitor of FYVE finger-containing phosphoinositide kinase (PIKFYVE, IC50 = 5.2 nM) that selectively inhibits interleukin-12 (IL-12) family inflammatory cytokine production (IC50s = 8, 99, and >10,000 nM for IL-12p70, IL-12p40, and TNF-alpha in stimulated human peripheral blood mononuclear cells...
| Keywords: | 2-[7-(4-morpholinyl)-2-(4-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]hydrazone, 3-methyl-benzaldehyde |
| Application: | 1-phosphatidylinositol 3-phosphate 5-kinase( PIKFYVE) inhibitor |
| CAS | 1232221-74-7 |
| MW: | 413.5 D |
From 56.00€
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YM201636
Item number: LKT-Y4802.1
YM201636 is an inhibitor of PIKfyve, decreasing the synthesis of phosphatidylinositol 3,5-disphosphate. YM210636 decreases muscular contraction-stimulated glucose uptake in vitro and induces autophagy-dependent neuronal death in other cellular models. Additionally, YM210636 inhibits endomembrane transport and...
| Application: | PIKfyve inhibitor |
| CAS | 371942-69-7 |
| MW: | 469.5 D |
From 202.00€
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MOMIPP
Item number: Cay39671-50
MOMIPP is an inhibitor of PIKfyve (IC50 = 5.05 nM). It selectively binds to PIKfyve over phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1C, Kds = 5.3 and >15,000 nM, respectively). MOMIPP (10 µM) induces vacuolization and cell lysis, markers of methuosis, and decreases the extracellular acidification...
| Keywords: | (2E)-3-(5-methoxy-2-methyl-1H-indol-3-yl)-1-(4-pyridinyl)-2-propen-1-one |
| Application: | PIKfyve inhibitor |
| CAS | 1363421-46-8 |
| MW: | 292.3 D |
From 57.00€
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YM201636 hydrochloride
Item number: SYN-1094-M001
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. YM-201636 is a cell-permeable and selective inhibitor of PIKfyve (IC(50) of 33nM). It disrupts retroviral budding from cells, apparently by interfering with the endosomal sorting complex required for transport (ESCRT) machinery. In adipocytes, YM-201636 also...
| Keywords: | YM-201636 |
| Application: | PIKfyve inhibitor |
| CAS | 371942-69-7 |
| MW: | 503,9 D |
From 154.00€
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Anti-PIKFYV
Item number: E-AB-10902.120
Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol...
| Keywords: | Anti-PIKfyve, Anti-PIKFYVE, Anti-KIAA0981, Anti-PIPkin-III, EC=2.7.1.150, Anti-Type III PIP kinase,... |
| Application: | IHC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 89.00€
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Anti-PIKFYV
Item number: E-AB-14682.120
Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol...
| Keywords: | Anti-PIKfyve, Anti-PIKFYVE, Anti-KIAA0981, Anti-PIPkin-III, EC=2.7.1.150, Anti-Type III PIP kinase,... |
| Application: | IHC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 89.00€
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Anti-PIKFYVE
Item number: ATA-HPA042604.100
Protein function: Dual specificity kinase implicated in myriad essential cellular processes such as maintenance of endomembrane homeostasis, and endocytic-vacuolar pathway, lysosomal trafficking, nuclear transport, stress- or hormone-induced signaling and cell cycle progression (PubMed:23086417). The PI(3,5)P2...
| Keywords: | Anti-PIKfyve, Anti-KIAA0981, Anti-PIPkin-III, Anti-Type III PIP kinase, Anti-Serine-protein kinase PIKFYVE,... |
| Application: | IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 369.00€
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Anti-PIKFYVE
Item number: CSB-PA003787.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-PIKfyve, Anti-KIAA0981, Anti-PIPkin-III, Anti-Type III PIP kinase, Anti-Serine-protein kinase PIKFYVE,... |
| Application: | ELISA, WB, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 126.00€
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Anti-PIKFYVE
Item number: CSB-PA072525.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Keywords: | Anti-PIKfyve, Anti-KIAA0981, Anti-PIPkin-III, Anti-Type III PIP kinase, Anti-Serine-protein kinase PIKFYVE,... |
| Application: | ELISA, WB, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
284.00€
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Anti-PIKFYVE
Item number: CSB-PA594945.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PIKFYVE. Antigen Species: Human
| Keywords: | Anti-PIKfyve, Anti-KIAA0981, Anti-PIPkin-III, Anti-Type III PIP kinase, Anti-Serine-protein kinase PIKFYVE,... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 167.00€
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Anti-PIKFYVE
Item number: CSB-PA924394.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PIKFYVE. Antigen Species: Human
| Keywords: | Anti-PIKfyve, Anti-KIAA0981, Anti-PIPkin-III, Anti-Type III PIP kinase, Anti-Serine-protein kinase PIKFYVE,... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 167.00€
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