122 products were found matching "K00898"!

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Mouse PDK2 (Pyruvate Dehydrogenase Kinase Isozyme 2) ELISA Kit
Mouse PDK2 (Pyruvate Dehydrogenase Kinase Isozyme 2)...

Item number: ELK-ELK7339.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PDK2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PDK2. Next,...
Keywords: Pdk2, PDH kinase 2, Pyruvate dehydrogenase kinase isoform 2, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme...
Application: ELISA
Species reactivity: mouse
365.00€ * From 328.50€ *
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Mouse PDK4 (Pyruvate Dehydrogenase Kinase Isozyme 4) ELISA Kit
Mouse PDK4 (Pyruvate Dehydrogenase Kinase Isozyme 4)...

Item number: ELK-ELK5009.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PDK4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PDK4. Next,...
Keywords: Pdk4, EC=2.7.11.2, Pyruvate dehydrogenase kinase isoform 4, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme...
Application: ELISA
Species reactivity: mouse
365.00€ * From 328.50€ *
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AZD 7545
AZD 7545

Item number: Cay19282-5

AZD 7545 is an inhibitor of pyruvate dehydrogenase (PDH) kinases (PDKs), resulting in an increase in PDH activity with an EC50 value of 5.2 nM for PDK2. It less potently inhibits PDK1 and PDK3 (IC50s = 87 and 600 nM, respectively). AZD 7545 stimulates pyruvate oxidation in rat hepatocytes (EC50 = 105 nM) and...
Keywords: 4-[[3-chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methyl-1-oxopropyl]amino]phenyl]sulfonyl]-N,N-dimethyl-benzamide
Application: Pyruvate dehydrogenase kinase (PDK) inhibitor
CAS 252017-04-2
MW: 478.9 D
From 54.00€ *
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Sodium dichloroacetate
Sodium dichloroacetate

Item number: AG-CR1-3684-G001

Mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor, consequently activating pyruvate dehydrogenase (PDH). Decreases glycolysis. Shifts pyruvate metabolism from glycolysis and lactate production to glucose oxidation in the mitochondria. Antitumor agent. Decreases tumor growth in vitro and in vivo. Induces...
Keywords: Dichloroacetic acid sodium salt, Bichloroacetic acid, BCA
Application: PDK inhibitor
CAS 2156-56-1
MW: 140.9 D
50.00€ * 45.00€ *
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VER-246608
VER-246608

Item number: Cay19182-1

VER-246608 is a pan-inhibitor of pyruvate dehydrogenase kinase (PDHK, IC50s = 35, 84, 40, and 91 nM for PDHK1, -2, -3, and -4, respectively). It is selective for PDHKs over heat shock protein 90 (Hsp90, IC50 = >100 µM), as well as a panel of 97 kinases at 10 µM. VER-246608 (10 and 20 µM) decreases the production of...
Keywords: N-[4-(2-chloro-5-methyl-4-pyrimidinyl)phenyl]-N-[[4-[[(2,2-difluoroacetyl)amino]methyl]phenyl]methyl]-2,4-dihydroxy-benzamide
Application: PDK1/2/3/4 inhibitor
CAS 1684386-71-7
MW: 553 D
From 44.00€ *
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AZD-7545
AZD-7545

Item number: AG-CR1-3692-M005

Potent and selective pyruvate dehydrogenase kinase 2 (PDK2) inhibitor (IC50=6.4nM), consequently increasing pyruvate dehydrogenase (PDH) activity. Less potent inhibitor towards PDK1 and PDK3 (IC50=87 and 600nM, respectively). Inhibitor of glycolysis. Antiobesity and antidiabetic agent. Improves blood glucose control...
Keywords: 4-[[3-Chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methyl-1-oxopropyl]amino]phenyl]sulfonyl]-N,N-dimethyl-benzamide
Application: Potent, selective pyruvate dehydrogenase kinase 2 (PDK2) inhibitor
CAS 252017-04-2
MW: 478.9 D
44.00€ * From 39.60€ *
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Anti-PDK2
Anti-PDK2

Item number: ARG55699.100

Protein function: Kinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle,...
Keywords: Anti-PDK2, Anti-PDKII, Anti-PDHK2, EC=2.7.11.2, Anti-PDH kinase 2, Anti-Pyruvate dehydrogenase kinase isoform 2,...
Application: FC, IHC (paraffin), WB
Host: Rabbit
Species reactivity: human, mouse, rat
584.00€ *
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Human PDK4 / Pyruvate Dehydrogenase Kinase Isozyme 4 ELISA Kit
Human PDK4 / Pyruvate Dehydrogenase Kinase Isozyme 4...

Item number: G-HUFI02722.96

Application: ELISA
Species reactivity: human
641.00€ *
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Anti-PDK2
Anti-PDK2

Item number: NSJ-R31101

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Pyruvate dehydrogenase kinase isoenzyme 2, is an enzyme that in humans is encoded by the PDK2 gene. To find human PDKs, Gudi et al.(1995) used oligonucleotide primers to screen a human liver cDNA library by PCR. The human PDK2 gene encodes a protein with a...
Keywords: Anti-PDK2, Anti-PDKII, Anti-PDHK2, EC=2.7.11.2, Anti-PDH kinase 2, Anti-Pyruvate dehydrogenase kinase isoform 2,...
Application: WB, IHC (paraffin), ICC
Host: Rabbit
Species reactivity: human, mouse, rat
755.00€ *
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Anti-PDK4
Anti-PDK4

Item number: NSJ-R32250

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Pyruvate dehydrogenase lipoamide kinase isozyme 4, mitochondrial is an enzyme that in humans is encoded by the PDK4 gene. This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This...
Keywords: Anti-PDK4, Anti-PDHK4, EC=2.7.11.2, Anti-Pyruvate dehydrogenase kinase isoform 4, Anti-[Pyruvate dehydrogenase...
Application: WB
Host: Rabbit
Species reactivity: human, rat
755.00€ *
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Human PDK4 (Pyruvate Dehydrogenase Kinase Isozyme 4) ELISA Kit
Human PDK4 (Pyruvate Dehydrogenase Kinase Isozyme 4)...

Item number: E-EL-H1092.96

The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of PDK4 in serum, plasma and other biological fluids. Detection Range: 1.56--100ng/mL. Sensitivity: 0.94ng/mL. Protein function: Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via...
Keywords: PDK4, PDHK4, EC=2.7.11.2, Pyruvate dehydrogenase kinase isoform 4, [Pyruvate dehydrogenase (acetyl-transferring)] kinase...
Application: ELISA
Species reactivity: human
483.00€ *
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Anti-PDK4
Anti-PDK4

Item number: NSJ-F50056-0.08ML

In 1X PBS, pH 7.4, with 0.09% sodium azide. PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism. Protein function: Kinase that plays a key role in regulation of glucose and fatty acid metabolism and...
Keywords: Anti-PDK4, Anti-PDHK4, EC=2.7.11.2, Anti-Pyruvate dehydrogenase kinase isoform 4, Anti-[Pyruvate dehydrogenase...
Application: WB, IHC, ELISA
Host: Rabbit
Species reactivity: human
From 326.00€ *
Review
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