96 products were found matching "K00826"!

A BCAT2 inhibitor (IC50 = 50nM in a cell-free assay), increases serum levels of leucine, isoleucine, and valine in mice at 10, 30, or 100 mg/kg when administered prior to an amino acid bolus, reduces tumor size and metastasis in a DU145 mouse xenograft model. SMILES:...

Branched-chain amino acid transferases (BCATs) catalyze reversible transamination of leucine, isoleucine, and valine branched-chain amino acids to their respective alpha-keto acids, liberating L-glutamate. Two forms of BCAT are present in mammals. Mitochondrial BCAT (BCATm) exists in most tissues throughout the...

Protein function: Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. [The UniProt Consortium]

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Branched-chain aminotransferase 2 is a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Branched-chain Aminotransferase 1 is also know as BCT1. The gene is highly expressed early in embryogenesis, and during organogenesis its expression is localized to the neural tube, the somites, and the mesonephric tubules. The gene is also expressed in several...

This gene encodes a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript variants encoding different isoforms have been found for this gene....

This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of...

Protein function: Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids. [The UniProt Consortium]

Protein function: Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. BCAT1, or Branched-chain Aminotransferase 1, is also know as BCT1. The BCAT1 gene is highly expressed early in embryogenesis, and during organogenesis its expression is localized to the neural tube, the somites, and the mesonephric tubules. The gene is also...

Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-386aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MKDCSNGCSA PFAGERGSEE VAETFRAKDL IITPATVLKE KPDPDSLVFG ATFTDHMLTV EWSSASGWEK PHIKPFGNLP IHPAASVLHY AVELFEGLKA FRGVDNKIRL FRPDLNMDRM CRSAVRTTLP...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 28-392aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: ASSSFKAADL QLEMTQKPHK KPGPGEPLVF GKTFTDHMLM VEWNDKGWGQ PRIQPFQNLT LHPASSSLHY SLQLFEGMKA FKGKDQQVRL FRPWLNMDRM LRSAMRLCLP...