150 products were found matching "K00789"!

S-(5'-Adenosyl)-L-methionine (SAM) is a methyl donor and cofactor. It is involved in several biological processes, including epigenetic regulation, post-translational modification of proteins, and metabolism. Formulations containing SAM have been used as dietary supplements.Formal Name:...

Protein function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate. [The UniProt Consortium]

PF-9366 is an inhibitor of methionine adenosyltransferase 2A (Mat2A, IC50 = 420 nM for S-adenosyl-L-methionine (SAM) production in an enzyme assay). It is selective for Mat2A over a panel of neurotransmitter transporters, phosphodiesterases, ion channels, and G protein-coupled receptors, as well as a panel of 39...

Description: AG-270 is an allosteric and orally active inhibitor of MAT2A. Target: Methionine Adenosyltransferase (MAT). Smiles: COc1ccc(cc1)-c1c(Nc2ccccn2)[nH]c2c(c(nn2c1=O)-c1ccccc1)C1=CCCCC1. References: Zenon Konteatis, et al. Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors...

Protein function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate. [The UniProt Consortium]

Human MAT2B, also known as Methionine Adenosyltransferase 2B, MAT2, and MAT II Beta. GenBank Accession No. NM_013283, a.a. 2-334 (end) with an N-terminal His-tag, expressed in an E. coli cell expression system. MW = 39 kDa.

Human MAT2A, also known as methionine adenosyltransferase II alpha, MAT2, S-adenosylmethionine synthase isoform type-2, and adoMet synthase 2. GenBank Accession No. NM_005911, a.a. 2-395 (end) with an N-terminal His-Avi-tag, expressed in an E. coli cell expression system. This protein is enzymatically biotinylated...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Methionine adenosyltransferase II, beta Protein function: Non-catalytic regulatory subunit of S-adenosylmethionine synthetase 2 (MAT2A), an enzyme that catalyzes the formation of S-...

Human MAT2A, also known as methionine adenosyltransferase II alpha, MAT2, and adoMet synthase 2. GenBank Accession No. NM_005911, a.a. 2-359 (end) with an N-terminal His-tag, expressed in an E. coli cell expression system. MW = 45 kDa.