33 products were found matching "K00682"!

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. The GGCT antibody targets Gamma-glutamylcyclotransferase, an enzyme encoded by the GGCT gene that participates in glutathione metabolism and cellular antioxidant defense. Gamma-glutamylcyclotransferase catalyzes the conversion of...

A prodrug form of N-glutaryl-L-alanine and a GGCT inhibitor, reduces the viability of UM-UC-3 and T24 cells (IC50s = 58.5 and 57 µM, respectively) and RT-112 cells, which have a high expression of GGCT (IC50 = 73.9 µM), enhances mitomycin C-induced growth of RT-112 cells, inhibits the proliferation of MCF-7 breast...

Protein function: Catalyzes the formation of 5-oxoproline from gamma- glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis. [The UniProt Consortium]

Protein function: Catalyzes the formation of 5-oxoproline from gamma- glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis. [The UniProt Consortium]

Protein function: Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium...

Protein function: Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium...

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-188aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MANSGCKDVT GPDEESFLYF AYGSNLLTER IHLRNPSAAF FCVARLQDFK LDFGNSQGKT SQTWHGGIAT IFQSPGDEVW GVVWKMNKSN LNSLDEQEGV KSGMYVVIEV KVATQEGKEI TCRSYLMTNY...

Description: GGCT belongs to the gamma-glutamylcyclotransferase family. It catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism. GGCT may play a significant role in glutathione homeostasis. GGCT also induces release of cytochrome c from mitochondria...

The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a...

Protein Construction: Recombinant Human gamma-Glutamylcyclotransferase is produced by our E.coli expression system and the target gene encoding Met1-Leu188 is expressed with a 6His tag at the N-terminus. Sequence: Met 1-Leu188. Fusion tag: N-6His Endotoxin: < 1.0 EU per µg as determined by the LAL method. Apparent...

Recombinant Human Gamma-Glutamylcyclotransferase is produced by our E.coli expression system and the target gene encoding Met1-Leu188 is expressed with a 6His tag at the N-terminus. Protein function: Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione...

Protein function: Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis. {ECO:0000269, PubMed:16765912, ECO:0000269, PubMed:18515354}. [The UniProt...