- Search results for K00665
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59 products were found matching "K00665"!
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Item number: Cay37545-10
FT113 is an inhibitor of fatty acid synthase (FASN, IC50 = 213 nM). It inhibits the proliferation of PC3 human prostate cancer and MV4-11 human acute myeloid leukemia cells (IC50s = 47 and 26 nM, respectively) and inhibits FASN activity in a 14C-acetate incorporation assay using BT474 human breast cancer cells (IC50...
Keywords: | [4-[4-(6-fluoro-2-benzoxazolyl)benzoyl]-1-piperazinyl](1-hydroxycyclopropyl)-methanone |
Application: | FASN inhibitor |
CAS | 1630808-89-7 |
MW: | 409.4 D |
From 86.00€
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Item number: ELK-ELK6016.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat FASN. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat FASN. Next,...
Keywords: | Fasn, Type I FAS, EC=3.1.2.14, Fatty acid synthase, Acyl-[acyl-carrier-protein] hydrolase, Enoyl-[acyl-carrier-protein]... |
Application: | ELISA |
Species reactivity: | rat |
From 365.00€
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Item number: ELK-ELK6328.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse FASN. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse FASN. Next,...
Keywords: | Fasn, Fatty acid synthase, Type I Fatty Acid Synthase, Acyl-[acyl-carrier-protein] hydrolase, Enoyl-[acyl-carrier-protein]... |
Application: | ELISA |
Species reactivity: | mouse |
From 365.00€
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Item number: ELK-ELK3009.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human FASN. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human FASN. Next,...
Keywords: | FAS, FASN, Fatty acid synthase, Type I fatty acid synthase, Acyl-[acyl-carrier-protein] hydrolase,... |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
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Item number: Cay16455-5
Malonyl coenzyme A is a coenzyme A (CoA, Cay-16147) derivative that is used in fatty acid and polyketide synthesis and in the transport of alpha-ketoglutarate across the mitochondrial membrane. Malonyl-CoA is formed by acetyl-CoA carboxylase-mediated carboxylation of acetyl-CoA (Cay-16160). Fatty acid synthase...
Keywords: | Malonyl-CoA, S-(hydrogen propanedioate) coenzyme A, lithium salt |
Application: | Fatty acid & polyketide synthesis intermediate |
CAS | 108347-84-8 |
MW: | 860.5 D |
From 60.00€
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Item number: A301-323A
Protein function: Fatty acid synthetase catalyzes the formation of long- chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein. [The UniProt Consortium]
Keywords: | Anti-FAS, Anti-FASN, EC=2.3.1.85, EC=2.3.1.38, EC=2.3.1.41, EC=3.1.2.14, EC=2.3.1.39, EC=4.2.1.59, EC=1.3.1.39,... |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: Cay20022-5
GSK2194069 is an inhibitor of fatty acid synthase (FASN) with an IC50 value of 7.7 nM in an assay detecting released CoA. It is a competitive inhibitor that is selective for the KR domain over the KS domain of FASN, with IC50 values of 29 and >10,000 nM, respectively, in vitro. GSK2194069 decreases incorporation of...
Keywords: | 4-[4-(5-benzofuranyl)phenyl]-5-[[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl]-2,4-dihydro-3H-1,2,4-triazol-3-one |
Application: | FASN inhibitor |
CAS | 1332331-08-4 |
MW: | 428.5 D |
From 43.00€
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Item number: Cay9000783-1
C75 is stable fatty acid synthase (FASN) inhibitor that when administered in racemic form leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice. C75 is also cytotoxic to many human cancer cell lines, an effect believed to be mediated by the...
Keywords: | (2R,3S)-C75, tetrahydro-4-methylene-2S-octyl-5-oxo-3R-furancarboxylic acid |
Application: | FAS inhibitor |
CAS | 1234694-20-2 |
MW: | 254.3 D |
From 229.00€
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Item number: Cay35703-1
TVB-2640 is an inhibitor of fatty acid synthase (FASN, IC50 = 0.5 µM). It inhibits infection of an infectious-clone-derived severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reporter virus in HEK293T cells expressing human angiotensin-converting enzyme 2 (ACE2, EC50 = 4 nM).Formal Name:...
Keywords: | Denifanstat, FASN-IN-2, Fatty Acid Synthase Inhibitor 2,... |
Application: | FASN inhibitor |
CAS | 1399177-37-7 |
MW: | 439.6 D |
From 76.00€
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Item number: A301-324A-T
Protein function: Fatty acid synthetase catalyzes the formation of long- chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein. [The UniProt Consortium]
Keywords: | Anti-FAS, Anti-FASN, EC=2.3.1.85, EC=2.3.1.38, EC=2.3.1.41, EC=3.1.2.14, EC=2.3.1.39, EC=4.2.1.59, EC=1.3.1.39,... |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: Cay19090-1
UCM05 is an inhibitor of fatty acid synthase that strongly suppresses the growth of human breast cancer cell lines (IC50 = 21 µM for SK-BR-3 cells). It does not alter carnitine palmitoyltransferase 1 activity or induce weight loss in mice. UCM05 can reduce cleavage of poly(ADP-ribose) polymerase, phosphorylation of...
Keywords: | G28UCM, 3,4,5-trihydr3,4,5-trihydroxy-benzoic acid 1,1'-(1,3-naphthalenediyl) ester |
Application: | Fatty acid synthase inhibitor |
CAS | 1094451-90-7 |
MW: | 464.4 D |
From 43.00€
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Item number: Cay20236-5
Icaritin is a flavonoid first isolated from the Chinese herb H. epimedii that demonstrates anticancer activity against a variety of tumor cell lines. It has been shown to inhibit fatty acid synthase, reducing IGF-1-induced activation of STAT3 in several melanoma cell lines.Formal Name:...
Keywords: | 3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one |
Application: | Anticancer agent, Fatty acid synthase inhibitor |
CAS | 118525-40-9 |
MW: | 368.4 D |
From 43.00€
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