55 products were found matching "K00643"!
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Hemin
Item number: TGM-T5515-1g
Description: Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer. Hemin has therapeutic activity in porphyrias by reducing heme deficiency in patients, thereby inhibiting delta-aminolevulinic acid synthetase activity through biochemical feedback. Target: Autophagy,...
| Keywords: | Hemin chloride |
| Application: | Targets 5-aminolevulinate synthase [EC:2.3.1.37] (E2.3.1.37, ALAS) |
| CAS | 16009-13-5 |
| MW: | 651.94 D |
From 42.00€
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ALAS1 Protein, Mouse, Recombinant (His & Myc)
Item number: TGM-TMPH-02477-100ug
Description: ALAS1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 72.3 kDa and the accession number is Q8VC19.
| Keywords: | 5-aminolevulinate synthase, non-specific, mitochondrial, 5-aminolevulinic acid synthase 1, ALAS-H, Delta-aminolevulinate... |
| MW: | 72.3 kD |
From 359.00€
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Givosiran
Item number: TGM-T39123-1mg
Description: Givosiran (ALN-AS1) is a small interfering RNA (siRNA) compound that specifically targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA (mRNA) to downregulate its expression, thereby inhibiting the accumulation of neurotoxic delta-aminolevulinic acid and porphobilinogen levels, with...
| Keywords: | Givosiran, ALN-AS1 |
| Application: | Targets 5-aminolevulinate synthase [EC:2.3.1.37] (E2.3.1.37, ALAS) |
| CAS | 1639325-43-1 |
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Anti-ALAS2
Item number: CSB-PA567068.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ALAS2. Antigen Species: Human
| Keywords: | Anti-ALASE, Anti-ALAS2, Anti-ALAS-E, EC=2.3.1.37, Anti-Delta-ALA synthase 2, Anti-5-aminolevulinic acid synthase 2,... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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Anti-ALAS1
Item number: CSB-PA797270.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ALAS1. Antigen Species: Human
| Keywords: | Anti-ALAS3, Anti-ALAS1, Anti-ALAS-H, EC=2.3.1.37, Anti-Delta-ALA synthase 1, Anti-5-aminolevulinic acid synthase 1,... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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Anti-ALAS1
Item number: CSB-PA929439.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ALAS1. Antigen Species: Human
| Keywords: | Anti-ALAS3, Anti-ALAS1, Anti-ALAS-H, EC=2.3.1.37, Anti-Delta-ALA synthase 1, Anti-5-aminolevulinic acid synthase 1,... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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5-Aminolevulinate synthase, erythroid-specific,...
Item number: CSB-EP001560HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 50-587aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: QIHLKATKAG GDSPSWAKGH CPFMLSELQD GKSKIVQKAA PEVQEDVKAF KTDLPSSLVS VSLRKPFSGP QEQEQISGKV THLIQNNMPG NYVFSYDQFF RDKIMEKKQD HTYRVFKTVN...
| Keywords: | ALAS2, ALASE, ALAS-E, EC=2.3.1.37, Delta-ALA synthase 2, Delta-aminolevulinate synthase 2, 5-aminolevulinic acid synthase... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 63.5 kD |
From 292.00€
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5-Aminolevulinate synthase, erythroid-specific,...
Item number: CSB-EP001560MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 50-587aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: QIHLKATKAG GDSPSWAKSH CPFMLSELQD RKSKIVQRAA PEVQEDVKTF KTDLLSTMDS TTRSHSFPSF QEPEQTEGAV PHLIQNNMTG SQAFGYDQFF RDKIMEKKQD HTYRVFKTVN...
| Keywords: | Alas2, ALAS-E, EC=2.3.1.37, Delta-ALA synthase 2, Delta-aminolevulinate synthase 2, 5-aminolevulinic acid synthase 2,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | mouse |
| MW: | 65.6 kD |
From 364.00€
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5-Aminolevulinate synthase, nonspecific, mitochondrial...
Item number: CSB-EP844984MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 57-642aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: QVKETPPANE KEKTAKAAVQ QAPDESQMAQ TPDGTQLPSG HPSPATSQGS GSKCPFLAAQ LSQTGSSVFR KASLELQEDV QEMHAVRKEA...
| Keywords: | Alas1, ALAS-H, EC=2.3.1.37, Delta-ALA synthase 1, Delta-aminolevulinate synthase 1, 5-aminolevulinic acid synthase 1,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | mouse |
| MW: | 72.3 kD |
From 364.00€
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ALAS2, active human recombinant protein
Item number: BPS-50270
Active human ALAS2 (aminolevulinate, delta-, synthase 2) (GenBank Accession No. NM_000032), (a.a. 136-553) with N-terminal His tag, MW = 46 kDa, expressed in an E. coli expression system.
| Keywords: | ALAS2, ALASE, ALAS-E, Delta-ALA synthase 2, Delta-aminolevulinate synthase 2, 5-aminolevulinic acid synthase 2,... |
| Application: | Enzyme kinetics, inhibitor screening |
| MW: | 46 kD |
775.00€
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Anti-ALAS2
Item number: E-AB-10763.120
The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms...
| Keywords: | Anti-ALAS2, Anti-ALASE, Anti-ALAS-E, EC=2.3.1.37, Anti-Delta-ALA synthase 2, Anti-5-aminolevulinic acid synthase 2,... |
| Application: | WB, ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 89.00€
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Anti-Alas1
Item number: ARG58186.100
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme, a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is...
| Keywords: | Anti-ALAS3, Anti-ALAS1, Anti-ALAS-H, EC=2.3.1.37, Anti-Delta-ALA synthase 1, Anti-Delta-aminolevulinate synthase 1,... |
| Application: | ICC, IF, WB |
| Host: | Rabbit |
| Species reactivity: | human |
658.00€
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