99 products were found matching "K00600"!

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. The SHMT2 antibody targets Serine hydroxymethyltransferase, mitochondrial, an enzyme encoded by the SHMT2 gene that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylenetetrahydrofolate. This reaction...

(±)-SHIN2 is a racemic mixture of (+)-SHIN2, a serine hydroxymethyltransferase 1 (SHMT1) and SHMT2 inhibitor, and (-)-SHIN2, the inactive isomer of (+)-SHIN2. Formal Name: 6-amino-1,4-dihydro-4-[3-(hydroxymethyl)-5-(5-hydroxy-1-pentyn-1-yl)phenyl]-3-methyl-4-(1-methylethyl)-pyrano[2,3-c]pyrazole-5-carbonitrile. CAS...

Protein function: Interconversion of serine and glycine (PubMed:8505317, PubMed:24698160). [The UniProt Consortium]

Protein function: Contributes to the de novo mitochondrial thymidylate biosynthesis pathway via its role in glycine and tetrahydrofolate metabolism. Thymidylate biosynthesis is required to prevent uracil accumulation in mtDNA (PubMed:21876188). Interconversion of serine and glycine (PubMed:25619277). Associates with...

Protein function: Interconversion of serine and glycine (PubMed:8505317, PubMed:24698160). [The UniProt Consortium]

Protein function: Interconversion of serine and glycine (PubMed:8505317, PubMed:24698160). [The UniProt Consortium]

Protein function: Contributes to the de novo mitochondrial thymidylate biosynthesis pathway via its role in glycine and tetrahydrofolate metabolism. Thymidylate biosynthesis is required to prevent uracil accumulation in mtDNA (PubMed:21876188). Interconversion of serine and glycine (PubMed:25619277). Associates with...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides...

Protein function: Catalyzes the cleavage of serine to glycine accompanied with the production of 5,10-methylenetetrahydrofolate, an essential intermediate for purine biosynthesis (PubMed:24075985, PubMed:29364879, PubMed:25619277). Serine provides the major source of folate one-carbon in cells by catalyzing the...

Protein function: Catalyzes the cleavage of serine to glycine accompanied with the production of 5,10-methylenetetrahydrofolate, an essential intermediate for purine biosynthesis (PubMed:24075985, PubMed:29364879, PubMed:25619277). Serine provides the major source of folate one-carbon in cells by catalyzing the...

Protein function: Interconversion of serine and glycine (PubMed:8505317, PubMed:24698160). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 78% and to rat: 75%

0.5mg/ml if reconstituted with 0.2ml sterile DI water. This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides...