39 products were found matching "K00541"!

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human NNMT. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human NNMT. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse NNMT. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse NNMT. Next,...

Nicotinamide is a precursor of NAD (Cay-16077) and NADP (Cay-10004675), which serve essential functions in modulating cellular redox status and controlling signaling and transcriptional events. 1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced by the action of nicotinamide...

N-Methylnicotinamide is an isomer of nicotinamide. N-methylnicotinamide (20 mg/animal) increases urinary excretion of nicotinamide, 1-methylnicotinamide (Cay-16604), 1-methyl-2-pyridone-5-carboxamide, and 1-methyl-4-pyridone-3-carboxamide in mice in similar ratios as those excreted following nicotinamide...

JBSNF-000088 is an inhibitor of nicotinamide N-methyltransferase (NNMT, IC50s = 1.8, 2.8, and 5 µM for human, monkey, and mouse NNMT, respectively). It inhibits NNMT and reduces 1-methyl-nicotinamide (MNA) levels in U2OS and 3T3L1 cells (IC50s = 1.6 and 6.3 µM, respectively). JBSNF-000088 (50 mg/kg) reduces visceral...

Nicotinamide N-Methyltransferase (NNMT) methylates nicotinamide and other pyridine containing compounds. NNMT transfers a methyl group from S-adenosylmethionine (SAM) to nitrogen N1 of nicotinamide to produce 1-methylnicotinamide (MNA) and S-adenosylhomocysteine. MNA is a messenger molecule that increases neurite...

Bisubstrate inhibitor 78 is an inhibitor of nicotinamide N-methyltransferase (NNMT, IC50 = 1.41 µM). It binds the NNMT active site in the binding pockets for the NNMT substrates S-adenosyl-L-methionine (SAM) and nicotinamide (Cay-11127). Bisubstrate inhibitor 78 is selective for NNMT over histone-lysine...

Protein function: Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds. [The UniProt Consortium]

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Nicotinamide N-methyltransferase Protein function: Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Nicotinamide N-methyltransferase Protein function: Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of...

Human NNMT1 also known as Nicotinamide N-Methyltransferase, GenBank Accession No. NM_006169, a.a. 1-264(full length), with C-terminal His-tag, expressed in an E. coli expression system. MW=30 kDa.