- Search results for K00507
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51 products were found matching "K00507"!
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Item number: ELK-ELK3716.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SCD. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SCD. Next,...
Keywords: | SCD, hSCD1, Delta-9 desaturase, Delta(9)-desaturase, Acyl-CoA desaturase, Fatty acid desaturase, Stearoyl-CoA desaturase |
Application: | ELISA |
Species reactivity: | human |
365.00€
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From 328.50€
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-10 %
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Item number: ELK-ELK6966.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat SCD. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat SCD. Next, Avidin...
Keywords: | Scd, Scd1, Delta-9 desaturase 1, Delta(9)-desaturase 1, Acyl-CoA desaturase 1, Fatty acid desaturase 1, Stearoyl-CoA... |
Application: | ELISA |
Species reactivity: | rat |
365.00€
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From 328.50€
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Item number: Cay37151-100
DUN41875 is an inhibitor of stearyol-CoA desaturase 1 (SCD1, IC50 = 11.8 nM for the rat enzyme). It increases tetramerization of soluble alpha-synuclein and reduces mutant alpha-synuclein incorporation into tetramers in BE(2)-M17 neuroblastoma cells expressing a mutant alpha-synuclein containing three...
Keywords: | SCD1 Inhibitor, Stearoyl-CoA Desaturase 1 Inhibitor, Stearoyl-Coenzyme A Desaturase 1 Inhibitor,... |
Application: | Stearoyl-CoA desaturase 1 inhibitor |
CAS | 1295541-87-5 |
MW: | 363.3 D |
From 119.00€
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Item number: Cay10012562-1
Stearoyl-CoA desaturase (SCD) catalyzes the committed step of the conversion of saturated, long-chain fatty acids to monounsaturated fatty acids. The SCD1 gene is thought to play a key role in lipid homeostasis and body weight regulation. Thus, modulating SCD1 activity pharmacologically may be a useful tool for...
Keywords: | 3-[4-(2-chloro-5-fluorophenoxy)-1-piperidinyl]-6-(5-methyl-1,3,4-oxadiazol-2-yl)-pyridazine |
Application: | SCD inhibitor |
CAS | 944808-88-2 |
MW: | 389.8 D |
From 106.00€
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Item number: Cay36704-1
GSK1940029 is a stearoyl-CoA desaturase (SCD) inhibitor. It increases palmitate-induced phosphorylation of p70 ribosomal S6 kinase 1 (p70S6K1) and lactate dehydrogenase (LDH) release from AML12 hepatocytes when used at a concentration of 20 µM. GSK1940029 (10 µM) also increases palmitate-induced increases in...
Keywords: | 1-[(3,4-dichlorophenyl)methyl]-N-[4-(hydroxymethyl)phenyl]-5-methyl-1H-1,2,3-triazole-4-carboxamide |
Application: | Stearoyl-CoA desaturase inhibitor |
CAS | 1150701-66-8 |
MW: | 391.3 D |
From 35.00€
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Item number: Cay19123-50
A-939572 inhibits stearoyl-CoA desaturase 1 (IC50 = 6.3 nM), a key enzyme for lipid metabolism that is expressed in human pluripotent stem cells (hPSCs). This compound has been used to induce cell death of hPSCs as well as to inhibit the proliferation of human non-small cell lung carcinoma H1299 cells in...
Keywords: | SCD1 Inhibitor, Stearoyl-CoA Desaturase 1 Inhibitor,... |
Application: | Stearoyl-CoA desaturase 1 inhibitor |
CAS | 1032229-33-6 |
MW: | 387.9 D |
From 70.00€
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Item number: Cay29421-10
MK-8245 is a liver-targeted inhibitor of stearoyl-CoA desaturase (SCD, IC50s = 3, 3, and 1 nM for rat, mouse, and human SCD1, respectively). It is selective for SCD1 over Delta5- and Delta6-desaturases (IC50s = >100,000 nM). MK-8245 (20-60 mg/kg) reduces the hepatic, but not Harderian gland, ratio of oleic acid to...
Keywords: | 5-[3-[4-(2-bromo-5-fluorophenoxy)-1-piperidinyl]-5-isoxazolyl]-2H-tetrazole-2-acetic acid |
Application: | Stearoyl-CoA desaturase inhibitor |
CAS | 1030612-90-8 |
MW: | 467.3 D |
From 92.00€
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Item number: Cay19379-10
SW203668 is an irreversible inhibitor of stearoyl-CoA desaturase (IC50 = 54 nM). It is selectively cytotoxic to H2122, H460, HCC44, and HCC95 cell lines that express cytochrome P450 (CYP) isoform CYP4F11 over eight other cancer cell lines that lack CYP4F11 in vitro (IC50s = 22-116 and >10,000 nM, respectively) and...
Keywords: | 4-(aminophenylmethyl)-N-(6-methoxy-2-benzothiazolyl)-benzamide, trifluoroacetate salt |
Application: | Stearoyl-CoA desaturase inhibitor prodrug |
CAS | 2117405-48-6 |
MW: | 503.5 D |
From 50.00€
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Item number: Cay16161-5
PluriSln 1 is an N-acyl phenylhydrazine derivative that inhibits stearoyl-CoA desaturase, a key enzyme for lipid metabolism that is expressed in human pluripotent stem cells (hPSCs). PluriSln 1 can selectively induce ER stress, attenuate protein synthesis, and induce apoptosis in hPSCs (EC50 = 2 µM) while sparing...
Keywords: | N'-phenyl-hydrazine-Isonicotinic acid, NSC 14613, 2-phenylhydrazide-4-pyridinecarboxylic acid |
Application: | Stearoyl-CoA desaturase inhibitor, HPSC apoptosis inducer |
CAS | 91396-88-2 |
MW: | 213.2 D |
From 84.00€
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Item number: Cay26735-25
Sterculic acid is a cyclopropene fatty acid that has been found in S. foetida. It is an inhibitor of Delta9-desaturase that decreases 9(Z)-myristoleic acid (Cay-9002461) and increases oleic acid (Cay-90260) and 9(Z),11(E)-conjugated linoleic acid (Cay-90140) levels in the milk of lactating ewes when administered at...
Keywords: | 2-octyl-1-cyclopropene-1-octanoic acid |
Application: | Cyclopropene fatty acid |
CAS | 738-87-4 |
MW: | 294.5 D |
530.00€
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Item number: Cay33349-1
MF438 is an inhibitor of stearoyl-CoA desaturase 1 (SCD1, IC50 = 2.3 nM for the rat enzyme), an enzyme that catalyzes the formation of a cis double bond at the ?9 position of stearoyl-CoA to produce oleoyl-CoA. It reduces spheroid formation in NCI H460 and patient-derived non-small cell lung cancer (NSCLC) cells in...
Keywords: | 3-(5-methyl-1,3,4-thiadiazol-2-yl)-6-[4-[2-(trifluoromethyl)phenoxy]-1-piperidinyl]-pyridazine |
Application: | Stearoyl-CoA desaturase inhibitor |
CAS | 921605-87-0 |
MW: | 421.4 D |
From 43.00€
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-10 %
Item number: AG-25A-0031-C100
Recognizes mouse SCD1. Detects a band of about 41kDa by Western Blot. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The enzyme is constitutively expressed in adipose tissue and is induced in liver in response to fat...
Keywords: | SCD1, Acyl-CoA Desaturase 1, Fatty Acid Desaturase 1 |
Application: | ELISA, WB |
Host: | Rabbit |
Species reactivity: | mouse |
286.00€
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257.40€
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