54 products were found matching "K00472"!

L-Ascorbic acid (vitamin C, Cay-14656) is essential for the synthesis of collagen, with deficiency resulting in scurvy. Notably, humans and other primates, guinea pigs, and certain other animals lack an enzyme necessary for vitamin C synthesis. L-Ascorbic acid 2-phosphate (AA2P) is a long-acting ascorbic acid...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat P4Ha1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat P4Ha1. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human P4Ha3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human P4Ha3. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human P4Ha2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human P4Ha2. Next,...

Deferoxamine is a bacterial siderophore that chelates iron. It is used to experimentally inhibit iron-dependent prolyl hydroxylases (EC50 = 17.8 µM), thus preventing the degradation of isoforms of hypoxia inducible factor during normoxia. Deferoxamine has applications in diseases that are characterized by high...

pythiDC is an inhibitor of collagen prolyl 4-hydroxylase (CP4H) containing the alpha(I) isoform (CP4H1, IC50 = 4 µM). It is selective for CP4H1 over hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2) at 10 µM.Formal Name: 6-(5-carboxy-2-thiazolyl)-3-pyridinecarboxylic acid. CAS Number: 1821370-71-1. Molecular...

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and...

1,4-DPCA ethyl ester is a synthetic precursor of the prolyl 4-hydroxylase inhibitor 1,4-DPCA (Cay-71220). 1,4-DPCA ethyl ester is also active against M. tuberculosis (MIC90 = 23.99 µM).Formal Name: 1,4-dihydro-4-oxo-1,10-phenanthroline-3-carboxylic acid, ethyl ester. CAS Number: 86443-19-8. Synonyms:...

Protein function: Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. [The UniProt Consortium]

Protein function: Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. [The UniProt Consortium]