The following products have been found matching your search "K00458": 24

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ML355
ML355

Item number: Cay18537-1

Platelet-type 12-lipoxygenase (12-LO, Cay-10341) catalyzes the formation of 12-HpETE (Cay-44570) from arachidonic acid (Cay-90010). It has been found to be expressed in various tumor cells as well as pancreatic islets and can be activated by inflammatory cytokines. It has also been implicated in the modulation of...
Keywords: N-2-benzothiazolyl-4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]-benzenesulfonamide
Application: 12-LO inhibitor
CAS 1532593-30-8
MW: 441.5 D
From 49.00€ *
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Baicalein
Baicalein

Item number: Cay70610-50

Baicalein is a flavonoid originally isolated from the roots of S. baicalensis that has diverse biological activities. It inhibits human platelet 12-lipoxygenase (12-LO) and human reticulocyte 15-LO-1 (IC50s = 0.64 and 1.6 µM, respectively) but is less potent at 15-LO-1 when the detergent Triton-X is present (IC50 =...
Keywords: 5,6,7-trihydroxyflavone
Application: Lipid peroxidation inhibitor
CAS 491-67-8
MW: 270.2 D
From 17.00€ *
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5,8,11-Eicosatriynoic Acid
5,8,11-Eicosatriynoic Acid

Item number: Cay90200-5

5,8,11-ETI is a nonselective inhibitor of lipoxygenases. It inhibits 12-LO in human platelets with an ID50 value of 24 µM. 5,8,11-ETI also inhibits A23187 and L-cysteine induced LTC4 biosynthesis in mouse mastocytoma cells with an ID50 value of 5 µM. At higher concentrations, 5,8,11-ETI also inhibits cyclooxygenases...
Keywords: 5,8,11-ETI, 5,8,11-eicosatriynoic acid
Application: LO inhibitor
CAS 13488-22-7
MW: 300.4 D
From 83.00€ *
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Human 12-LO (Arachidonate 12-Lipoxygenase) CLIA Kit
Human 12-LO (Arachidonate 12-Lipoxygenase) CLIA Kit

Item number: G-HUES01277.96

ELISA Type: CLIA. Sensitivity: 37.5 pg/mL. Range: 62.5--4000 pg/mL. Protein function: Catalyzes the regio and stereo-specific incorporation of a single molecule of dioxygen into free and esterified polyunsaturated fatty acids generating lipid hydroperoxides that can be further reduced to the corresponding hydroxy...
Keywords: 12LO, ALOX12, 12S-LOX, EC=3.3.2.-, 12S-lipoxygenase, Lipoxin synthase 12-LO, Linoleate 13S-lipoxygenase, Platelet-type...
Application: CLIA
Reactivity: Human
629.00€ *
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Human 12-LO (Arachidonate 12-Lipoxygenase) ELISA Kit
Human 12-LO (Arachidonate 12-Lipoxygenase) ELISA Kit

Item number: G-HUES03311.96

ELISA Type: Sandwich. Sensitivity: 0.188ng/mL. Range: 0.313--20ng/mL. Protein function: Catalyzes the regio and stereo-specific incorporation of a single molecule of dioxygen into free and esterified polyunsaturated fatty acids generating lipid hydroperoxides that can be further reduced to the corresponding hydroxy...
Keywords: 12LO, ALOX12, 12S-LOX, EC=3.3.2.-, 12S-lipoxygenase, Lipoxin synthase 12-LO, Linoleate 13S-lipoxygenase, Platelet-type...
Application: Sandwich ELISA
Reactivity: Human
566.00€ *
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Mouse 12-LO (Arachidonate 12-Lipoxygenase) ELISA Kit
Mouse 12-LO (Arachidonate 12-Lipoxygenase) ELISA Kit

Item number: G-MOES01636.96

ELISA Type: Sandwich. Sensitivity: 0.469ng/mL. Range: 0.781--50ng/mL. Protein function: Catalyzes the regio and stereo-specific incorporation of a single molecule of dioxygen into free and esterified polyunsaturated fatty acids generating lipid hydroperoxides that can be further reduced to the corresponding hydroxy...
Keywords: P-12LO, Alox12, 12S-LOX, Alox12p, EC=3.3.2.-, 12S-lipoxygenase, Lipoxin synthase 12-LO, Linoleate 13S-lipoxygenase,...
Application: Sandwich ELISA
Reactivity: Mouse
576.00€ *
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CAY10698
CAY10698

Item number: Cay18582-1

Platelet-type 12-lipoxygenase (12-LO, Cay-10341) catalyzes the formation of 12-HpETE (Cay-44570) from arachidonic acid (Cay-90010). It has been found to be expressed in various tumor cells as well as pancreatic islets and can be activated by inflammatory cytokines. It has also been implicated in the modulation of...
Keywords: 4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]-N-2-thiazolyl-benzenesulfonamide
Application: 12-LO inhibitor
CAS 684236-01-9
MW: 391.5 D
From 32.00€ *
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NEW
12-LO (Arachidonate 12-Lipoxygenase) BioAssay(TM) ELISA Kit (Human)
12-LO (Arachidonate 12-Lipoxygenase) BioAssay(TM) ELISA...

Item number: 381758.96

Sample Type:, Serum, Plasma, Biological Fluids, Intended Use: This BioAssay(TM) kit is a sandwich ELISA for in vitro quantitative measurement of 12-LO in human serum, plasma and other biological fluids, Sensitivity: 0.188ng/mL, Range: 0.313-20ng/mL, Specificity: Recognizes natural and some recombinant Human 12-LO,...
Keywords: 12LO, 12S-LOX, EC=3.3.2.-, 12S-lipoxygenase, Lipoxin synthase 12-LO, Linoleate (13S)-lipoxygenase, Platelet-type...
Application: ELISA
Reactivity: Human
714.00€ *
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NEW
12-LO (Arachidonate 12-Lipoxygenase) BioAssay(TM) ELISA Kit (Mouse)
12-LO (Arachidonate 12-Lipoxygenase) BioAssay(TM) ELISA...

Item number: 381759.96

Sample Type:, Serum, Plasma, Biological Fluids, Intended Use: This BioAssay(TM) kit is a sandwich ELISA for in vitro quantitative measurement of 12-LO in Mouse serum, plasma and other biological fluids, Sensitivity: 0.469ng/mL, Range: 0.781-50ng/mL, Specificity: Recognizes natural and some recombinant Mouse 12-LO....
Keywords: Alox12, P-12LO, 12S-LOX, Alox12p, EC=3.3.2.-, 12S-lipoxygenase, Lipoxin synthase 12-LO, Linoleate (13S)-lipoxygenase,...
Application: ELISA
Reactivity: Mouse
714.00€ *
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Human 12-LO / ALOX12 ELISA Kit
Human 12-LO / ALOX12 ELISA Kit

Item number: G-HUFI01663.96

Application: ELISA
Reactivity: Human
629.00€ *
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Anti-12 Lipoxygenase
Anti-12 Lipoxygenase

Item number: NSJ-R30558

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Arachidonate 12-lipoxygenase, is an enzyme that in humans is encoded by the ALOX12 gene. By fluorescence in situ hybridization, the ALOX12 gene is located in band 17p13.1. The gene consists of 14 exons with 13 introns and spans approximately 15 kb of...
Keywords: Anti-12LO, Anti-ALOX12, Anti-12S-LOX, EC=3.3.2.-, EC=1.13.11.31, Anti-12S-lipoxygenase, Anti-Lipoxin synthase 12-LO,...
Application: WB
Reactivity: Human
503.00€ *
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Human 12-LO (Arachidonate 12-Lipoxygenase) ELISA Kit
Human 12-LO (Arachidonate 12-Lipoxygenase) ELISA Kit

Item number: E-EL-H2445.96

The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of 12-LO in serum, plasma and other biological fluids. Detection Range: 0.31--20ng/mL. Sensitivity: 0.19ng/mL. Protein function: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified...
Keywords: 12LO, ALOX12, 12S-LOX, EC=3.3.2.-, EC=1.13.11.31, 12S-lipoxygenase, Lipoxin synthase 12-LO, Platelet-type lipoxygenase 12,...
Application: ELISA
Reactivity: Human
587.00€ *
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