40 products were found matching "K00457"!

Nitisinone is a nitrobenzene inhibitor of HPPD, an enzyme involved in tyrosine degradation. Nitisinone is clinically used to slow the effects of hereditary type 1 tyrosinemia and as a potential treatment for alkaptonuria.

In 1X PBS, pH 7.4, with 0.09% sodium azide. HPD is an enzyme in the catabolic pathway of tyrosine. This protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Protein function: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat HPD. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat HPD. Next, Avidin...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human HPD. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HPD. Next,...

Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway. Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3...

White crystalline powder. Soluble in acetone, ethyl acetate, methanol or ethanol. Insoluble in water. Thiocarbamate herbicide with fungicidal activity. Inhibits 4-hydroxyphenyl-pyruvatedioxygenase (4-HPPD) in plants that causes bleaching. And targets squalene-epoxidase in sterol biosynthesis in fungus. Compound can...

Homogentisic acid is a phenolic acid and intermediate in the catabolism of aromatic amino acids, including phenylalanine and tyrosine. It is formed in excess during alkaptonuria, whereas excess deposition of homogentisic acid in connective tissues produces ochronosis.Formal Name: 2,5-dihydroxy-benzeneacetic acid....

Yellow crystalline powder. Soluble in methanol. Insoluble in water. Amide herbicide pigment inhibitor. Mode of action is through inhibition of 4-hydroxyphenyl-pyruvatedioxygenase (4-HPPD) that causes bleaching. Compound can be used as analytical reference material.

The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms...

Protein function: Key enzyme in the degradation of tyrosine. [The UniProt Consortium]

Nitisinone-13C6 is intended for use as an internal standard for the quantification of nitisinone (Cay-17924) by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway. Nitisinone...