46 products were found matching "K00207"!

Dihydrothymine is a metabolite of the pyrimidine nucleobase thymine. It is formed from thymine by dihydropyrimidine dehydrogenase (DPD). Dihydrothymine can also be produced from thymine by UV radiation. Levels of dihydrothymine are elevated during the epithelial-to-mesenchymal transition (EMT) in human mammary...

Eniluracil is an irreversible inhibitor of dihydropyrimidine dehydrogenase (DPD, Ki = 1.6 µM), the rate-determining enzyme in the catabolism of pyrimidines, including 5-fluorouracil (Cay-14416). It inhibits liver DPD and elevates plasma pyrimidine levels in rats (ED50s = 1.8 and 10 µg/kg, respectively). Eniluracil...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Dihydropyrimidine Dehydrogenase, also called DPD, is an enzyme that in humans is encoded by the DPYD gene. The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. DPYD (Dihydropyrimidine Dehydrogenase), also called DPD, is an enzyme that in humans is encoded by the DPYD gene. The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine...

Protein function: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil. [The UniProt Consortium]

White powder. Soluble in methanol. Beta-Aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine. beta-Aminoisobutyric acid occurs in two isomeric forms and both enantiomers of beta-Aminoisobutyric acid can be detected in human urine and plasma. In plasma, the...

Protein function: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil. [The UniProt Consortium]

Gimeracil is an inhibitor of dihydropyrimidine dehydrogenase (DYPD, Ki = 0.36 µM), the rate limiting enzyme in the catabolism of pyrimidines, including 5-fluorouracil (5-FU, Cay-14416). It inhibits the degradation of 5-FU in rat liver extracts (IC50 = 0.1 µM). Gimeracil inhibits homologous recombination and enhances...

Protein function: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil. [The UniProt Consortium]