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Anti-Recombinant SPR, clone A748
Anti-Recombinant SPR, clone A748

Item number: E-AN302028L.100

SPR can catalyze the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.Defects in SPR are the cause of dystonia DOPA-responsive due to sepiapterin reductase deficiency (DRDSPRD). In the majority of cases, patients manifest progressive psychomotor retardation,...
Keywords: Anti-SPR, Anti-Sepiapterin reductase, Recombinant SPR Monoclonal Antibody
Application: WB, IHC
Host: Rabbit
Species reactivity: human
From 304.00€ *
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SPRi 3
SPRi 3

Item number: Cay30950-1

SPRi 3 is an inhibitor of sepiapterin reductase (SPR), an enzyme that catalyzes the formation of tetrahydrobiopterin (BH4), with IC50 values of 62 and 14 nM for the recombinant human and rat enzymes, respectively. It is selective for SPR over GTP cyclohydroxylase 1 (GCH1) in primary mouse dorsal root ganglia sensory...
Keywords: N-[2-(5-hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxy-acetamide
Application: Sepiapterin reductase (SPR) inhibitor
CAS 1292285-54-1
MW: 262.3 D
From 67.00€ *
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Anti-SPR
Anti-SPR

Item number: E-AB-13034.120

This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on...
Keywords: Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase, SPR Polyclonal Antibody
Application: WB, IHC, ELISA
Host: Rabbit
Species reactivity: human
From 89.00€ *
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Anti-SPR
Anti-SPR

Item number: NSJ-F52016-0.08ML

In 1X PBS, pH 7.4, with 0.09% sodium azide. SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A...
Keywords: Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase, SPR Antibody
Application: WB, ELISA
Host: Rabbit
Species reactivity: human, mouse
From 361.00€ *
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Anti-SPR
Anti-SPR

Item number: E-AB-16217.120

This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on...
Keywords: Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase, SPR Polyclonal Antibody
Application: WB, IHC, ELISA
Host: Rabbit
Species reactivity: human, mouse
From 89.00€ *
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Anti-SPR
Anti-SPR

Item number: ATA-HPA039505.100

Protein function: Catalyzes the final one or two reductions in tetra- hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 74% and to rat: 73%
Keywords: Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase
Application: ICC, IHC, WB
Host: Rabbit
Species reactivity: human
From 369.00€ *
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Human SPR (Sepiapterin Reductase) ELISA Kit
Human SPR (Sepiapterin Reductase) ELISA Kit

Item number: ELK-ELK3702.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SPR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SPR. Next,...
Keywords: SPR, Sepiapterin reductase
Application: ELISA
Species reactivity: human
From 374.00€ *
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Sepiapterin reductase (SPR), human, recombinant
Sepiapterin reductase (SPR), human, recombinant

Item number: CSB-EP022605HU.1

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-261aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MEGGLGRAVC LLTGASRGFG RTLAPLLASL LSPGSVLVLS ARNDEALRQL EAELGAERSG LRVVRVPADL GAEAGLQQLL GALRELPRPK GLQRLLLINN AGSLGDVSKG FVDLSDSTQV NNYWALNLTS...
Keywords: SPR, EC=1.1.1.153, Sepiapterin reductase, Recombinant Human Sepiapterin reductase (SPR)
Application: Activity not tested
Expressed in: E.coli
Origin: human
MW: 32 kD
From 292.00€ *
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Anti-SPR
Anti-SPR

Item number: CSB-PA214577.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SPR. Antigen Species: Human
Keywords: Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase, OTTHUMP00000160199 antibody, SDR38C1 antibody, Sepiapterin reductase...
Application: ELISA, WB, IHC
Host: Rabbit
Species reactivity: human, mouse
From 167.00€ *
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Anti-SPR
Anti-SPR

Item number: CSB-PA262747.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SPR. Antigen Species: Human
Keywords: Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase, OTTHUMP00000160199 antibody, SDR38C1 antibody, Sepiapterin reductase...
Application: ELISA, WB, IHC
Host: Rabbit
Species reactivity: human
From 167.00€ *
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SPR inhibitor 3
SPR inhibitor 3

Item number: TGM-T16924-10mg

Description: SPR inhibitor 3 is an effective sepiapterin reductase inhibitor. SPR inhibitor 3 decreases neuropathic and inflammatory pain through a reduction of BH4 levels. SPR inhibitor 3 shows a high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a...
Keywords: SPRi3
Application: SPR inhibitor
CAS 1292285-54-1
MW: 262.3 D
From 64.00€ *
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NEW
Anti-SPR [4F5] Monoclonal Antibody -Knockout Validated
Anti-SPR [4F5] Monoclonal Antibody -Knockout Validated

Item number: G-AGMB06743.100

[KO] SPR Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin [The Uniprot Consortium]
Keywords: Anti-SPR, Anti-Sepiapterin reductase
Application: WB, IHC-P, FC
Host: Mouse
Species reactivity: human, rat
From 378.00€ *
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